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AKR7A1
Known as:
aldehyde reductase AKR7A1
National Institutes of Health
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1 relation
Broader (1)
Aldehyde Reductase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Aldo‐keto reductase‐7A protects liver cells and tissues from acetaminophen‐induced oxidative stress and hepatotoxicity
M. E. Ahmed
,
Tao Wang
,
+6 authors
James Y. Yang
Hepatology
2011
Corpus ID: 28744507
Aldo‐keto reductase‐7A (AKR7A) is an enzyme important for bioactivation and biodetoxification. Previous studies suggested that…
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2009
2009
Transgenic expression of aflatoxin aldehyde reductase (AKR7A1) modulates aflatoxin B1 metabolism but not hepatic carcinogenesis in the rat.
B. Roebuck
,
Denise N Johnson
,
+9 authors
T. Sutter
Toxicological sciences : an official journal of…
2009
Corpus ID: 142077
In both experimental animals and humans, aflatoxin B(1) (AFB(1)) is a potent hepatic toxin and carcinogen against which a variety…
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2008
2008
Protection against aflatoxin B1-induced cytotoxicity by expression of the cloned aflatoxin B1-aldehyde reductases rat AKR7A1 and human AKR7A3.
Sridevi Bodreddigari
,
Laundette Knight Jones
,
+6 authors
T. Sutter
Chemical research in toxicology
2008
Corpus ID: 6694018
The reduction of the aflatoxin B 1 (AFB 1) dialdehyde metabolite to its corresponding mono and dialcohols, catalyzed by aflatoxin…
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2008
2008
Aldo-keto reductase 1C2 is essential for 1-nitropyrene's but not for benzo[a]pyrene's induction of p53 phosphorylation and apoptosis.
Jyan-Gwo J. Su
,
Pei-Jyuan Liao
,
Mincong Huang
,
Wen-Cheng Chu
,
Shin-Chang Lin
,
Y. Chang
Toxicology
2008
Corpus ID: 24667250
2004
2004
Detoxication of the environmental pollutant acrolein by a rat liver aldo-keto reductase.
R. Gardner
,
S. Kazi
,
E. Ellis
Toxicology letters
2004
Corpus ID: 30657285
2003
2003
Characterization of the rat aflatoxin B1 aldehyde reductase gene, AKR7A1. Structure and chromosomal localization of AKR7A1 as well as identification of antioxidant response elements in the gene…
E. Ellis
,
C. M. Slattery
,
J. Hayes
Carcinogenesis
2003
Corpus ID: 7023025
Rat aflatoxin B(1) aldehyde reductase (called AFAR1 or AKR7A1) is a member of the aldo-keto reductase 7 family, which metabolizes…
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2003
2003
Substrate specificity of mouse aldo-keto reductase AKR7A5.
A. Hinshelwood
,
G. McGarvie
,
E. Ellis
Chemico-biological interactions
2003
Corpus ID: 21026174
2002
2002
Characterisation of a novel mouse liver aldo‐keto reductase AKR7A5
A. Hinshelwood
,
G. McGarvie
,
E. Ellis
FEBS letters
2002
Corpus ID: 32753461
2002
2002
The Crystal Structure of Rat Liver AKR7A1
E. Kozma
,
Elaine H. Brown
,
E. Ellis
,
A. Lapthorn
The Journal of Biological Chemistry
2002
Corpus ID: 13917354
The structure of the rat liver aflatoxin dialdehyde reductase (AKR7A1) has been solved to 1.38-Å resolution. Although it shares a…
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Highly Cited
1999
Highly Cited
1999
cDNA cloning, expression and activity of a second human aflatoxin B1-metabolizing member of the aldo-keto reductase superfamily, AKR7A3.
L. Knight
,
T. Primiano
,
J. Groopman
,
T. Kensler
,
T. Sutter
Carcinogenesis
1999
Corpus ID: 36072388
The aflatoxin B1 (AFB1) aldehyde metabolite of AFB1 may contribute to the cytotoxicity of this hepatocarcinogen via protein…
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