AKR1A1 gene

Known as: ALR, ALDEHYDE REDUCTASE, AKR1A1 
This gene plays a role in the reduction of biogenic and xenobiotic aldehydes.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1992-2018
024619922018

Papers overview

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2013
2013
Transcription factor NF-E2-related factor 2 (NRF2) plays a crucial role in the cellular defense against oxidative/electrophilic… (More)
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2012
2012
The main obstacle to cure tumors by radiotherapy has been ascribed to tumor radioresistance. To determine the mechanisms… (More)
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2009
2009
In contrast to hepatocytes, there is only limited information about the expression and activities of enzymes participating in… (More)
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2008
2008
Human aldo-keto reductase (AKR) 1C3 (type 2 3alpha-hydroxysteroid dehydrogenase/type 5 17beta-hydroxysteroid dehydrogenase… (More)
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2007
2007
Carbonyl reduction is a main but undesired metabolic pathway of the anti-cancer drug daunorubicin (DRC). The resulting alcohol… (More)
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2005
2005
(+/-)-7,8-Dihydroxy-7,8-dihydrobenzo[a]pyrene (BP-7,8-diol), a proximate carcinogen derived from benzo[a]pyrene (BP) requires… (More)
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2001
2001
Polycyclic aromatic hydrocarbons (PAHs) are metabolized to trans-dihydrodiol proximate carcinogens by human epoxide hydrolase (EH… (More)
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Highly Cited
1999
Highly Cited
1999
Complementary DNA clones encoding human aflatoxin B(1) aldehyde reductase (AKR7A2), aldehyde reductase (AKR1A1), aldose reductase… (More)
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1996
1996
An NADPH-dependent aldehyde reductase (ALR) isolated from a red yeast, Sporobolomyces salmonicolor, catalyzes the reduction of a… (More)
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