AKR1C3 gene

Known as: HAKRB, PGFS, KIAA0119 
This gene is involved in the conversion of aldehydes and ketones to alcohols.
National Institutes of Health

Papers overview

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2015
2015
The introduction of enzalutamide and abiraterone has led to improvement in the treatment of metastatic castration-resistant… (More)
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Review
2013
Review
2013
Aberrant androgen receptor (AR) activation is the major driver of castrate resistant prostate cancer (CRPC). CRPC is ultimately… (More)
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Highly Cited
2010
Highly Cited
2010
Genomic and transcriptomic alterations that affect cellular processes, such as cell proliferation, differentiation, apoptosis and… (More)
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Highly Cited
2008
Highly Cited
2008
Aromatic amines (AAs) and polycyclic aromatic hydrocarbons (PAHs) are carcinogens present in tobacco smoke and functional… (More)
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2006
2006
Type 2 3alpha-hydroxysteroid dehydrogenase (3alpha-HSD) is a multi-functional enzyme that possesses 3alpha-, 17beta- and 20alpha… (More)
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Highly Cited
2004
Highly Cited
2004
Lung cancer rates among men and particularly among women, almost all of whom are non-smokers, in Xuan Wei County, China are among… (More)
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2004
2004
Recent evidence suggests that progesterone metabolites play important roles in regulating breast cancer. Previous studies have… (More)
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Highly Cited
2003
Highly Cited
2003
We and others have demonstrated expression of the aldo-keto reductase AKR1C3 in myeloid leukemia cell lines and that inhibitors… (More)
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Highly Cited
2001
Highly Cited
2001
Olfactory lamellae of teleosts contain two morphologically different types of olfactory receptor neurons (ORNs): ciliated ORNs… (More)
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Highly Cited
2000
Highly Cited
2000
The kinetic parameters, steroid substrate specificity and identities of reaction products were determined for four homogeneous… (More)
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