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Acetylcysteine
Known as:
Acetylcysteine [Chemical/Ingredient]
, Acid, Mercapturic
, L-Cysteine, N-acetyl-
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A synthetic N-acetyl derivative of the endogenous amino acid L-cysteine, a precursor of the antioxidant enzyme glutathione. Acetylcysteine…
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National Institutes of Health
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Related topics
Related topics
48 relations
Narrower (29)
1,4-dihydroxynonene mercapturic acid
1-methylpyrenylmercapturic acid
2-(acetylcysteine)-N-isopropylacetanilide
3-hydroxy-1-methylpropylmercapturic acid
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Acute Kidney Tubular Necrosis
Antidote
Bronchitis
Drug toxicity
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Broader (3)
Amino Acids, Sulfur
Cysteine
Free Radical Scavengers
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Prednisone, azathioprine, and N-acetylcysteine for pulmonary fibrosis.
G. Raghu
,
K. Anstrom
,
T. King
,
J. Lasky
,
F. Martinez
New England Journal of Medicine
2012
Corpus ID: 8248970
BACKGROUND A combination of prednisone, azathioprine, and N-acetylcysteine (NAC) has been widely used as a treatment for…
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Highly Cited
2008
Highly Cited
2008
trans-Dimethanolbis(1,1,1-trifluoro-5,5-dimethylhexane-2,4-dionato)zinc(II)
Gerald O. Hunter
,
Matthew Zeller
,
B. D. Leskiw
Acta Crystallographica Section E
2008
Corpus ID: 60675884
The title compound, [Zn(C8H10F3O2)2(CH4O)2], is a dimethanol coordinated zinc complex with the acetyl acetonate derivative 1,1,1…
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Review
2005
Review
2005
High-dose acetylcysteine in idiopathic pulmonary fibrosis.
M. Demedts
,
J. Behr
,
+20 authors
M. Montanari
New England Journal of Medicine
2005
Corpus ID: 30279834
BACKGROUND Idiopathic pulmonary fibrosis is a chronic progressive disorder with a poor prognosis. METHODS We conducted a double…
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Review
2004
Review
2004
Glutathione metabolism and its implications for health.
Guoyao Wu
,
Yun-Zhong Fang
,
Sheng Yang
,
J. Lupton
,
N. Turner
Journal of NutriLife
2004
Corpus ID: 4485589
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione…
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Review
2003
Review
2003
Molecular mechanisms of N-acetylcysteine actions
M. Zafarullah
,
W. Li
,
Judith Sylvester
,
Mushtaq Ahmad
Cellular and Molecular Life Sciences (CMLS)
2003
Corpus ID: 9621730
Abstract. Oxidative stress generated by an imbalance between reactive oxygen species (ROS) and antioxidants contributes to the…
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Highly Cited
2000
Highly Cited
2000
Prevention of radiographic-contrast-agent-induced reductions in renal function by acetylcysteine.
Martin Tepel
,
M. van der Giet
,
Carola Schwarzfeld
,
U. Laufer
,
D. Liermann
,
W. Zidek
New England Journal of Medicine
2000
Corpus ID: 11268991
BACKGROUND Radiographic contrast agents can cause a reduction in renal function that may be due to reactive oxygen species…
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Highly Cited
1993
Highly Cited
1993
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
D. Hockenbery
,
Z. Oltvai
,
Xiao-Ming Yin
,
C. Milliman
,
S. Korsmeyer
Cell
1993
Corpus ID: 37004175
Highly Cited
1991
Highly Cited
1991
Reactive oxygen intermediates as apparently widely used messengers in the activation of the NF‐kappa B transcription factor and HIV‐1.
R. Schreck
,
Peter Rieberl
,
P. Baeuerle
EMBO Journal
1991
Corpus ID: 37291279
Hydrogen peroxide and oxygen radicals are agents commonly produced during inflammatory processes. In this study, we show that…
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Highly Cited
1974
Highly Cited
1974
Glutathione S-transferases. The first enzymatic step in mercapturic acid formation.
W. Habig
,
M. Pabst
,
W. Jakoby
Journal of Biological Chemistry
1974
Corpus ID: 20671605
Abstract The purification of homogeneous glutathione S-transferases B and C from rat liver is described. Kinetic and physical…
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Highly Cited
1967
Highly Cited
1967
Spectroscopic determination of tryptophan and tyrosine in proteins.
H. Edelhoch
Biochemistry
1967
Corpus ID: 15393074
A rapid method for the determination of tryptophan in proteins is presented. It is based on ab- sorbance measurements at 288 and…
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