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A 127722

Known as: A-127722, A-127722.5 
National Institutes of Health

Related topics

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2 relations
ABT 627

Broader (1)

atrasentan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Endothelin and the regulation of uteroplacental perfusion in nitric oxide synthase inhibition-induced fetal growth restriction.
2004
2004
Effects of endothelin ETA receptor antagonism on granulocyte and lymphocyte accumulation in LPS‐induced inflammation
Endothelin peptides play active roles in different aspects of inflammation. This study investigates the contribution of… 
Highly Cited
2003
Highly Cited
2003
RhoA-Rho kinase mediates synergistic ET-1 and phenylephrine contraction of rat corpus cavernosum.
Maintenance of the detumescent state of the penis is believed to involve the actions of several vasoconstrictors. However, our… 
2002
2002
Endothelin ET(B) receptor-mediated mechanisms involved in oleic acid-induced acute lung injury in mice.
The receptors underlying the endothelin-dependent component of lung plasma extravasation and leucocyte infiltration induced by… 
2001
2001
Enhanced endothelin-1 response and receptor expression in small mesenteric arteries of insulin-resistant rats.
Hyperinsulinemia, a primary feature of insulin resistance, is associated with increased endothelin-1 (ET-1) activity. This study… 
Highly Cited
2000
Highly Cited
2000
Contractile and arrhythmic effects of endothelin receptor agonists in human heart in vitro: blockade with SB 209670.
It is known that binding sites with endothelin(A) (ET)(A) and ET(B) receptor characteristics coexist in human heart but little is… 
1998
1998
Vascular endothelin-1 expression and effect of an endothelin ETA antagonist on structure and function of small arteries from stroke-prone spontaneously hypertensive rats.
There is some evidence that the endothelin (ET) system may participate in blood pressure elevation and in vascular hypertrophy in… 
Highly Cited
1998
Highly Cited
1998
Chronic oral endothelin type A receptor antagonism in experimental heart failure.
Endothelin-1 (ET-1) is a cardiovascular peptide that binds to two distinct receptors, ET(A) and ET(B), resulting in systemic and… 
Highly Cited
1998
Highly Cited
1998
Endothelin A receptor blockade alleviates hypertension and renal lesions associated with chronic nitric oxide synthase inhibition.
Unopposed actions of vasoconstrictors, such as angiotensin, play an important role in the effects of chronic nitric oxide… 
1998
1998
Role of endothelin ET(A) receptors in the hypertension produced by 4-day L-nitroarginine methyl ester and cyclosporine treatment.
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