Skip to search formSkip to main contentSkip to account menu
  • Publications
  • Influence
Endothelial function and dysfunction: testing and clinical relevance.
TLDR
Current understanding of endothelial biology in health and disease, the strengths and weaknesses of current testing strategies, and their potential applications in clinical research and patient care are summarized.
View on PubMed
Endothelial progenitor cell dysfunction: a novel concept in the pathogenesis of vascular complications of type 1 diabetes.
TLDR
It is demonstrated that adverse metabolic stress factors in type 1 diabetes are associated with reduced EPC numbers and angiogenicity, and hypothesize that EPC dysfunction contributes to the pathogenesis of vascular complications intype 1 diabetes.
View on PubMed
Olmesartan for the delay or prevention of microalbuminuria in type 2 diabetes.
TLDR
Olmesartan was associated with a delayed onset of microalbuminuria, even though blood-pressure control in both groups was excellent according to current standards.
View on PubMed
Sympathetic activation markedly reduces endothelium-dependent, flow-mediated vasodilation.
View on PubMed
Stent placement in patients with atherosclerotic renal artery stenosis and impaired renal function: a randomized trial.
TLDR
Stent placement with medical treatment in patients with ARAS had no clear effect on progression of impaired renal function but led to a small number of significant procedure-related complications.
View on PubMed
Cellular regulation of endothelial nitric oxide synthase.
  • R. Govers, T. Rabelink
  • Biology, Chemistry
    American journal of physiology. Renal physiology
  • 1 February 2001
TLDR
The present review focuses on the complex regulation of eNOS within the endothelial cell.
View on PubMed
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy.
View on PubMed
Tetrahydrobiopterin restores endothelial function in hypercholesterolemia.
TLDR
Restoration of endothelial dysfunction by tetrahydrobiopterin suppletion in hypercholesterolemic patients is demonstrated and both the attenuated L-mono-methyl-arginine- induced vasoconstriction as well as the impaired serotonin-induced vasodilation were restored in patients during tetrahytochemical infusion.
View on PubMed
Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade.
TLDR
Selective ET(A) receptor antagonism causes vasodilatation of human forearm resistance vessels in vivo, which appears to result in major part from an increase in nitric oxide generation.
View on PubMed
Expression of connective tissue growth factor in human renal fibrosis.
TLDR
The results indicate that CTGF may be a common growth factor involved in renal fibrosis, and an increase in the number of cells expressing CTGF mRNA was observed at sites of chronic tubulointerstitial damage, which correlated with the degree of damage.
View on PubMed
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License