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5-Hydroxytryptamine Receptor 1A, human
Known as:
HTR1A protein, human
, 5-Hydroxytryptamine Receptor 1A
, G-21
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5-hydroxytryptamine receptor 1A (422 aa, ~46 kDa) is encoded by the human HTR1A gene. This protein is involved in both serotonin binding and…
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National Institutes of Health
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Related topics
Related topics
13 relations
G Protein-Coupled Receptor Genes
G Protein-Coupled Receptor Signaling
HTR1A gene
Integral Membrane Proteins
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Broader (1)
Receptor, Serotonin, 5-HT1A
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Role of the C-terminal di-leucine motif of 5-HT1A and 5-HT1B serotonin receptors in plasma membrane targeting
D. Carrel
,
M. Hamon
,
M. Darmon
Journal of Cell Science
2006
Corpus ID: 29115964
The 5-HT1A and 5-HT1B serotonin receptors exhibit different subcellular localizations in neurons. Evidence has been reported that…
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Review
2005
Review
2005
Differential changes in serotonin 5-HT1A and 5-HT2 receptor binding in patients with chronic schizophrenia
T. Hashimoto
,
N. Kitamura
,
+5 authors
C. Tanaka
Psychopharmacology
2005
Corpus ID: 6237874
Serotonin 5-HT1A and 5-HT2 receptors were examined in the postmortem brains of controls and patients with chronic schizophrenia…
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Highly Cited
2004
Highly Cited
2004
Desensitization of 5-HT1A Receptors by 5-HT2A Receptors in Neuroendocrine Neurons in Vivo
Yahong Zhang
,
T. Gray
,
+9 authors
L. D. van de Kar
Journal of Pharmacology and Experimental…
2004
Corpus ID: 11085581
An imbalance between serotonin-2A (5-HT2A) and 5-HT1A receptors may underlie several mood disorders. The present studies…
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Highly Cited
2001
Highly Cited
2001
5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential.
W. Koek
,
B. Vacher
,
+4 authors
F. Colpaert
European Journal of Pharmacology
2001
Corpus ID: 26032223
1998
1998
Rapid activation of sodium-proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades.
M. Garnovskaya
,
Y. Mukhin
,
John R. Raymond
Biochemical Journal
1998
Corpus ID: 35726279
These experiments tested the hypothesis that signalling elements involved in the activation of the extracellular signal-regulated…
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Highly Cited
1997
Highly Cited
1997
5-hydroxytryptamine receptor subtype messenger RNAs in human dorsal root ganglia: a polymerase chain reaction study
P. Pierce
,
G. Xie
,
T. Meuser
,
S. Peroutka
Neuroscience
1997
Corpus ID: 962014
Highly Cited
1993
Highly Cited
1993
Central 5-HT1A receptors inhibit adrenocortical secretion.
J. E. Welch
,
G. E. Farrar
,
A. Dunn
,
D. Saphier
Neuroendocrinology
1993
Corpus ID: 3323597
Serotonin (5-HT) is generally considered to serve a facilitatory role in the regulation of adrenocortical secretion. Numerous…
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Highly Cited
1992
Highly Cited
1992
Antipeptide antibodies against the 5-HT1A receptor
E. Azmitia
,
I. Yu
,
H. M. Akbari
,
Nancy M. Kheck
,
P. Whitaker-Azmitia
,
D. Marshak
Journal of Chemical Neuroanatomy
1992
Corpus ID: 8717986
1992
1992
Structure-activity relationship studies of central nervous system agents. 5. Effect of the hydrocarbon chain on the affinity of 4-substituted 1-(3-chlorophenyl)piperazines for 5-HT1A receptor site.
J. Mokrosz
,
M. Pietrasiewicz
,
B. Duszyńska
,
M. Cegła
Journal of Medicinal Chemistry
1992
Corpus ID: 43891839
The effect of the hydrocarbon chain of the model 4-substituted 1-(3-chlorophenyl)piperazines 12-31 on their affinity for 5-HT1A…
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1989
1989
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
G. Martin
,
R. J. Elgin
,
+7 authors
Malcom K. Scott
Journal of Medicinal Chemistry
1989
Corpus ID: 923209
Generally, antipsychotic agents are dopamine receptor blocking agents that also block conditioned avoidance responding (CAR) in…
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