5-Hydroxytryptamine Receptor 1A, human

Known as: HTR1A protein, human, 5-Hydroxytryptamine Receptor 1A, G-21 
5-hydroxytryptamine receptor 1A (422 aa, ~46 kDa) is encoded by the human HTR1A gene. This protein is involved in both serotonin binding and… (More)
National Institutes of Health

Related topics

Related topics

13 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingHTR1A geneIntegral Membrane Proteins
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Broader (1)

Receptor, Serotonin, 5-HT1A

Papers overview

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Highly Cited
2007
Highly Cited
2007
Curcumin reverses impaired hippocampal neurogenesis and increases serotonin receptor 1A mRNA and brain-derived neurotrophic factor expression in chronically stressed rats
Curcuma longa is a major constituent of Xiaoyao-san, the traditional Chinese medicine, which has been used to effectively manage… (More)
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Highly Cited
2006
Highly Cited
2006
Response to fluoxetine and serotonin 1A receptor (C-1019G) polymorphism in Taiwan Chinese major depressive disorder
Serotonin systems appear to play a key role in the pathogenesis of major depression and the therapeutic mechanisms of… (More)
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Review
2004
Review
2004
The therapeutic role of 5-HT1A and 5-HT2A receptors in depression.
The selective serotonin reuptake inhibitors (SSRIs) are the most frequently prescribed antidepressant drugs, because they are… (More)
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Highly Cited
2001
Highly Cited
2001
Serotonin 1A Receptors, Serotonin Transporter Binding and Serotonin Transporter mRNA Expression in the Brainstem of Depressed Suicide Victims
Suicide and depression are associated with reduced serotonergic neurotransmission. In suicides, there is a reduction in serotonin… (More)
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Highly Cited
1998
Highly Cited
1998
Tracer kinetic modeling of the 5-HT1A receptor ligand [carbonyl-11C]WAY-100635 for PET.
[Carbonyl-11C]WAY-100635 is a promising PET radioligand for the 5-HT1A receptor, having demonstrated more favorable… (More)
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Highly Cited
1995
Highly Cited
1995
A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635.
WAY-100635 (N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2- pyridinyl)cyclohexanecarboxamide trihydrochloride) is an achiral… (More)
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Review
1993
Review
1993
Subordination stress: Behavioral, brain, and neuroendocrine correlates
In mixed-sex rat groups consistent asymmetries in offensive and defensive behaviors of male dyads are associated with the… (More)
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Highly Cited
1992
Highly Cited
1992
Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding.
In order to localize the cells expressing 5-HT1A receptors in the rat brain, we used in situ hybridization histochemistry to… (More)
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Highly Cited
1992
Highly Cited
1992
5-Hydroxytryptamine 1a receptor agonists block prepulse inhibition of acoustic startle reflex.
Presentation of a nonstartling stimulus (prepulse) 100 msec before a startle-eliciting auditory stimulus (pulse) reduces startle… (More)
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Highly Cited
1988
Highly Cited
1988
The genomic clone G-21 which resembles a β-adrenergic receptor sequence encodes the 5-HT1A receptor
The recent cloning of the complementary DNAs and/or genes for several receptors linked to guanine nucleotide regulatory proteins… (More)
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