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5-Hydroxytryptamine Receptor 1A, human

Known as: HTR1A protein, human, 5-Hydroxytryptamine Receptor 1A, G-21 
5-hydroxytryptamine receptor 1A (422 aa, ~46 kDa) is encoded by the human HTR1A gene. This protein is involved in both serotonin binding and… 
National Institutes of Health

Related topics

Related topics

13 relations
G Protein-Coupled Receptor GenesG Protein-Coupled Receptor SignalingHTR1A geneIntegral Membrane Proteins

Broader (1)

Receptor, Serotonin, 5-HT1A

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2006
2006
Role of the C-terminal di-leucine motif of 5-HT1A and 5-HT1B serotonin receptors in plasma membrane targeting
The 5-HT1A and 5-HT1B serotonin receptors exhibit different subcellular localizations in neurons. Evidence has been reported that… 
Review
2005
Review
2005
Differential changes in serotonin 5-HT1A and 5-HT2 receptor binding in patients with chronic schizophrenia
Serotonin 5-HT1A and 5-HT2 receptors were examined in the postmortem brains of controls and patients with chronic schizophrenia… 
Highly Cited
2004
Highly Cited
2004
Desensitization of 5-HT1A Receptors by 5-HT2A Receptors in Neuroendocrine Neurons in Vivo
An imbalance between serotonin-2A (5-HT2A) and 5-HT1A receptors may underlie several mood disorders. The present studies… 
Highly Cited
2001
Highly Cited
2001
5-HT1A receptor activation and antidepressant-like effects: F 13714 has high efficacy and marked antidepressant potential.
1998
1998
Rapid activation of sodium-proton exchange and extracellular signal-regulated protein kinase in fibroblasts by G protein-coupled 5-HT1A receptor involves distinct signalling cascades.
These experiments tested the hypothesis that signalling elements involved in the activation of the extracellular signal-regulated… 
Highly Cited
1997
Highly Cited
1997
5-hydroxytryptamine receptor subtype messenger RNAs in human dorsal root ganglia: a polymerase chain reaction study
Highly Cited
1993
Highly Cited
1993
Central 5-HT1A receptors inhibit adrenocortical secretion.
Serotonin (5-HT) is generally considered to serve a facilitatory role in the regulation of adrenocortical secretion. Numerous… 
Highly Cited
1992
Highly Cited
1992
Antipeptide antibodies against the 5-HT1A receptor
1992
1992
Structure-activity relationship studies of central nervous system agents. 5. Effect of the hydrocarbon chain on the affinity of 4-substituted 1-(3-chlorophenyl)piperazines for 5-HT1A receptor site.
The effect of the hydrocarbon chain of the model 4-substituted 1-(3-chlorophenyl)piperazines 12-31 on their affinity for 5-HT1A… 
1989
1989
Activity of aromatic substituted phenylpiperazines lacking affinity for dopamine binding sites in a preclinical test of antipsychotic efficacy.
Generally, antipsychotic agents are dopamine receptor blocking agents that also block conditioned avoidance responding (CAR) in… 
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