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HTR1A gene

Known as: 5-HYDROXYTRYPTAMINE RECEPTOR 1A, BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, SEROTONIN 5-HT-1A RECEPTOR 
This gene is involved in serotonin-dependent signaling.
National Institutes of Health

Related topics

Related topics

8 relations
5-Hydroxytryptamine Receptor 1A, humanG Protein-Coupled Receptor SignalingHTR1B geneLigand Binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Suppression of Serotonin Neuron Firing Increases Aggression in Mice
Numerous studies link decreased serotonin metabolites with increased impulsive and aggressive traits. However, although… 
Highly Cited
2010
Highly Cited
2010
Polymorphisms of the HTR1a allele are linked to frontal brain electrical asymmetry
Highly Cited
2009
Highly Cited
2009
Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression
The HTR1A −1019C>G genotype was associated with major depression in the Utah population. Linkage analysis on Utah pedigrees with… 
Highly Cited
2009
Highly Cited
2009
Serotonin 5-HT2 and 5-HT1A-like receptors differentially modulate aggressive behaviors in Drosophila melanogaster
Highly Cited
2009
Highly Cited
2009
Effects of HTR1A C(-1019)G on amygdala reactivity and trait anxiety.
CONTEXT Serotonin 1A (5-hydroxytryptamine 1A [5-HT(1A)]) autoreceptors mediate negative feedback inhibition of serotonergic… 
2009
2009
Functional 5‐HT1a receptor polymorphism selectively modulates error‐specific subprocesses of performance monitoring
Our study investigates the dependence of response monitoring and error detection on genetic influences modulating the… 
Highly Cited
2007
Highly Cited
2007
Interaction between 5-HT1A and BDNF genotypes increases the risk of treatment-resistant depression
SummarySeveral studies have linked 5-HT1A C1019G and BDNF G196A (Val66Met) gene polymorphisms to major depressive disorder (MDD… 
1999
1999
Cross-Modulation of Synaptic Plasticity by β-Adrenergic and 5-HT1A Receptors in the Rat Basolateral Amygdala
Neurotransmitter receptors are often colocalized in a neuron with other receptors, and activation of one receptor can either… 
Highly Cited
1988
Highly Cited
1988
Reversal of helpless behavior in rats by putative 5-HT1A agonists
Highly Cited
1987
Highly Cited
1987
Differential effects of serotonin (5-HT1A and 5-HT2) agonists and antagonists on renin and corticosterone secretion.
The present study was designed to investigate the effect of distinct serotonin (5-HT1A and 5-HT2) agonists and antagonists on… 
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