Noradrenergic mechanisms in neurodegenerative diseases: a theory
- M. Marien, F. Colpaert, A. Rosenquist
- Biology, PsychologyBrain Research Reviews
- 1 April 2004
Effects of locus coeruleus lesions on parkinsonian signs, striatal dopamine and substantia nigra cell loss after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in monkeys: A possible role for the locus…
- M. Mavridis, A. Degryse, A. Lategan, M. Marien, F. Colpaert
- Biology, PsychologyNeuroscience
- 31 December 1991
Pharmacological characteristics of tremor, rigidity and hypokinesia induced by reserpine in rat
- F. Colpaert
- Biology, PsychologyNeuropharmacology
- 1 September 1987
Opiate States of Memory: Receptor Mechanisms
- L. Slot, F. Colpaert
- Biology, PsychologyJournal of Neuroscience
- 1 December 1999
It appears that a particular magnitude of μ opiate receptor activation produces a state to which a memory trace can be confined in a highly selective manner.
Noradrenaline provides long‐term protection to dopaminergic neurons by reducing oxidative stress
- J. Troadec, M. Marien, P. Michel
- BiologyJournal of Neurochemistry
- 1 October 2001
The model of mesencephalic cultures supports the concept that central noradrenergic mechanisms have a neuroprotective role, perhaps in part by reducing oxidative stress.
The Alpha2-Adrenoceptor Antagonist Dexefaroxan Enhances Hippocampal Neurogenesis by Increasing the Survival and Differentiation of New Granule Cells
- P. Rizk, Julio Salazar, T. Debeir
- Biology, PsychologyNeuropsychopharmacology
- 1 June 2006
By promoting the survival of new endogenously formed neurons, dexefaroxan treatment represents a potential therapeutic strategy for maintaining adult neurogenesis in neurodegenerative conditions, such as Alzheimer's disease, that affect the hippocampus.
Noradrenaline depletion exacerbates MPTP-induced striatal dopamine loss in mice.
- M. Marien, M. Briley, F. Colpaert
- Biology, ChemistryEuropean Journal of Pharmacology
- 4 June 1993
NMDA antagonists make learning and recall state-dependent.
- A. Jackson, W. Koek, F. Colpaert
- Psychology, BiologyBehavioural Pharmacology
- 1 August 1992
The data do not support the widely held notion that NMDA antagonists produce deficits in memory or retention; instead, at doses considerably lower than those impairing acquisition, NMda antagonists produce a state upon which the recall of the newly learned response is dependent.
Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway.
- P. Chopin, F. Colpaert, M. Marien
- Biology, PsychologyJournal of Pharmacology and Experimental…
- 1 February 1999
The effects on apomorphine-induced circling indicate an influence of alpha-2 adrenoceptor compounds on nigrostriatal neurotransmission at sites downstream from the dopaminergic neurons themselves.
Discriminative stimulus properties of benzodiazepines, barbiturates and pharmacologically related drugs; relation to some intrinsic and anticonvulsant effects.
- F. Colpaert, L. Desmedt, P. Janssen
- Psychology, BiologyEuropean Journal of Pharmacology
- 1 May 1976
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