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12-hydroxy-5,8,10-heptadecatrienoic acid

Known as: 12-HHT, 5,8,10-heptadecatrienoic acid, 12-hydroxy-, 12-L-hydroxy-5,8,10-heptadecatrienoic acid 
 
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Mammals have at least two receptors for LTB4; high-affinity BLT1 and low-affinity BLT2, both of which are GPCRs. 12-HHT serves as… Expand
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2010
2010
BackgroundNutritional factors play a major role in cancer initiation and development. Dietary polyunsaturated fatty acids (PUFAs… Expand
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Highly Cited
2008
Highly Cited
2008
Activated blood platelets and macrophages metabolize prostaglandin H2 into thromboxane A2 and 12(S)-hydroxyheptadeca-5Z, 8E, 10E… Expand
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2007
2007
We investigated the effects of certain dietary polyunsaturated fatty acids (PUFAs) and related eicosanoids on the growth and… Expand
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2000
2000
Cyclooxygenases catalyze the oxygenation of arachidonic acid to prostaglandin endoperoxides. Cyclooxygenase-2- and the xenobiotic… Expand
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Highly Cited
1996
Highly Cited
1996
Production of 12-L-hydroxy-5, 8, 10-heptadecatrienoic acid (12-HHT) from platelets and bleeding times were studied in 32 males… Expand
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1990
1990
The nonsteroidal anti-inflammatory drugs are presumed to produce their analgesic effects by inhibiting the cyclooxygenase… Expand
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1988
1988
Metabolites of arachidonic acid are potent modulators of many biological events, and their release from macrophages appears to… Expand
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Highly Cited
1985
Highly Cited
1985
Abnormalities in glomerular function have been observed frequently in the early stages of both clinical and experimental diabetes… Expand
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1981
1981
The imidazole derivative UK-37 248, a thromboxane synthetase inhibitor, reduces the in-vitro formation of thromboxane B2 and… Expand
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