1-nitrosopyrene
National Institutes of Health
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To study the role of nucleotide excision repair in the induction of intrachromosomal homologous recombination in mammalian cells…
The carcinogenic activities of 1-nitropyrene, a mutagenic component of diesel exhaust, and its reduced derivatives 1…
1-Nitropyrene has been shown in bacterial assays to be the principal mutagenic agent in diesel emission particulates. It has also…
The cytotoxic and mutagenic effects of 1-nitropyrene (1-NP) and its reduced metabolite 1-nitrosopyrene (1-NOP) were determined in…
1,6-Dinitropyrene and 1,8-dinitropyrene are environmental contaminants which are mutagenic in bacteria and cultured mammalian…
Eight nitropolycyclic aromatic hydrocarbons (PAHs), including 1- and 4-nitropyrene, 1,3-, 1,6- and 1,8-dinitropyrene, 7-nitrobenz…
Chinese hamster ovary cells were exposed to N-hydroxy-2-aminofluorene, N-hydroxy-N'-acetylbenzidine and 1-nitrosopyrene, and the…
The microbial metabolism of the mutagenic and carcinogenic polycyclic nitroaromatic hydrocarbon, 1-nitropyrene, has been studied…
The metabolism of 1-nitropyrene by rat liver 9000 X g supernatant was investigated. Under aerobic conditions, ring oxidation to 1…