C. Cerniglia

Publications414
h-index79
Citations22,781
Highly Influential Citations913
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Biodegradation of polycyclic aromatic hydrocarbons
The intent of this review is to provide an outline of the microbial degradation of polycyclic aromatic hydrocarbons. A catabolically diverse microbial community, consisting of bacteria, fungi and… Expand
Degradation of Phenanthrene and Anthracene by Cell Suspensions of Mycobacterium sp. Strain PYR-1
TLDR
The data point to the existence, next to already known routes for both gram-negative and gram-positive bacteria, of alternative pathways that might be due to the presence of different dioxygenases or to a relaxed specificity of the same dIOxygenase for initial attack on polycyclic aromatic hydrocarbons. Expand
Microbial metabolism of polycyclic aromatic hydrocarbons.
  • C. Cerniglia
  • Chemistry, Medicine
  • Advances in applied microbiology
  • 1984
TLDR
Studies on PAH metabolism are entering a new era; biochemical genetic techniques such as gene cloning and transposon mutagenesis will provide new insight into the biochemistry and regulation of PAH degradative pathways. Expand
Complete and Integrated Pyrene Degradation Pathway in Mycobacterium vanbaalenii PYR-1 Based on Systems Biology
TLDR
Analysis of pyrene metabolism in M. vanbaalenii PYR-1 indicates that this bacterium degrades pyrene to central intermediates through o-phthalate and the beta-ketoadipate pathway. Expand
Pyrene degradation by a Mycobacterium sp.: identification of ring oxidation and ring fission products
TLDR
The degradation of pyrene by pure cultures of a Mycobacterium sp. Expand
PCR detection and quantitation of predominant anaerobic bacteria in human and animal fecal samples
PCR procedures based on 16S rRNA gene sequences specific for 12 anaerobic bacteria that predominate in the human intestinal tract were developed and used for quantitative detection of these species… Expand
Effects of pH on the degradation of phenanthrene and pyrene by Mycobacterium vanbaalenii PYR-1
TLDR
An acidic pH seemed to render the mycobacterial cells more permeable to hydrophobic substrates, and the non-K-region polycyclic aromatic hydrocarbon oxidation might be a significant burden to the cell due to the accumulation of toxic metabolites. Expand
Microbial metabolism of polycyclic aromatic hydrocarbons: isolation and characterization of a pyrene-degrading bacterium
TLDR
The mycobacterium mineralized pyrene when grown in a mineral salts medium supplemented with nutrients but was unable to utilize pyrene as a sole source of carbon and energy. Expand
Molecular cloning, overexpression, purification, and characterization of an aerobic FMN-dependent azoreductase from Enterococcus faecalis.
TLDR
AzoA is the first aerobic azoreductase to be identified and characterized from human intestinal gram-positive bacteria, and was not only able to decolorize Methyl red, but was also able to convert sulfonated azo dyes Orange II, Amaranth, Ponceau BS, and PonceAU S. Expand
Biochemical and molecular characterization of an azoreductase from Staphylococcus aureus, a tetrameric NADPH-dependent flavoprotein.
TLDR
Azo1 represents the first azoreductase to be identified and characterized from human skin microflora and requires NADPH, but not NADH, as an electron donor for its activity. Expand
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