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1,6-dinitropyrene

Known as: DINITROPYRENE, 1,6-, Pyrene, 1,6-dinitro- 
A synthetic, yellow crystalline solid that is insoluble in water and moderately soluble in toluene. It is not used for any commercial applications… 
National Institutes of Health

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Broader (2)

MutagensPyrenes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1995
1995
DNA adduct formation and T-lymphocyte mutation induction in F344 rats implanted with tumorigenic doses of 1,6-dinitropyrene.
Diesel emissions are known to induce tumors in experimental animals and are suspected of being carcinogenic in humans. Of the… 
1993
1993
Mutagenic activity of urban air samples and its modulation by chili extracts.
1991
1991
Kinds of mutations found when a shuttle vector containing adducts of 1,6-dinitropyrene replicates in human cells.
To gain insight into the mechanisms by which carcinogens induce mutations in human cells, we have been comparing the frequency… 
1990
1990
Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes.
NADPH-fortified human liver microsomes were examined with regard to ability to detoxicate several chemicals that do not require… 
Highly Cited
1988
Highly Cited
1988
DNA binding by 1-nitropyrene and 1,6-dinitropyrene in vitro and in vivo: effects of nitroreductase induction.
1-Nitropyrene, the predominant nitropolycyclic aromatic hydrocarbon found in diesel exhaust, is a mutagen and tumorigen. 1,6… 
1987
1987
Carcinogen-DNA adduct formation in the lungs and livers of preweanling CD-1 male mice following administration of [3H]-6-nitrochrysene, [3H]-6-aminochrysene, and [3H]-1,6-dinitropyrene.
6-Nitrochrysene (NC) and 6-aminochrysene (AC) have been shown to be potent lung and liver carcinogens when administered in… 
1986
1986
Mutagenicity of the photochemical reaction products of pyrene with nitrogen dioxide.
Highly Cited
1985
Highly Cited
1985
Identification and quantification of highly mutagenic nitroacetoxypyrenes and nitrohydroxypyrenes in diesel-exhaust particles.
1985
1985
Assessment of chemically induced DNA repair in primary cultures of human bronchial epithelial cells.
1982
1982
The clastogenic activity of dinitropyrenes in a rat-liver epithelial cell line.
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