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visilizumab

Known as: Anti CD3, Anti-CD3 Antibody 
A humanized, non-Fc receptor (FcR)-binding IgG2 monoclonal antibody (MoAb) directed against CD3 with potential immunosuppressive activity… 
National Institutes of Health

Related topics

Related topics

10 relations

Narrower (2)

Anti-CD3 AntibodyMonoclonal Antibody HuM291

Broader (2)

Antibodies, Monoclonal, HumanizedMonoclonal Antibodies
CD3 AntigensMuromonab-CD3NuvionPositive Regulation of Apoptosis

Papers overview

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Highly Cited
2007
Highly Cited
2007
Inhibition of human ovarian tumor growth by cytokine-induced killer cells
Despite the recent improvement in the treatment of ovarian cancer, this disease is still leading cause of cancer death in women… 
2005
2005
Analysis of the susceptibility of CD57+ T cells to CD3‐mediated apoptosis
After stimulation with anti‐CD3 antibody in vitro, CD57+ T cells showed a greater susceptibility to apoptosis than CD57–αβT cell… 
2002
2002
Ethanol enhances activation-induced caspase-3 dependent cell death in T lymphocytes.
BACKGROUND Clinical and experimental studies have shown that an important deleterious consequence of excessive alcohol… 
2000
2000
T‐Lymphocyte Subpopulations Do Not Express Identical Combinations of Interleukin‐2 Receptor Chains in the Early Phase of Their Activation and Proliferation
Owing to the contrasting observations in the field of interleukin(IL)‐2 receptor research, the expression of IL‐2 receptor chains… 
1999
1999
Interferon-gamma production by T lymphocytes from renal cell carcinoma patients: evidence of impaired secretion in response to interleukin-12.
Interleukin-12 (IL-12) is a heterodimeric cytokine that enhances the cytolytic activity, proliferation, and interferon-gamma (IFN… 
1993
1993
Proenzyme from of cathepsin L produced by thymic epithelial cells promotes proliferation of immature thymocytes in the presence of IL-1, IL-7, and anti-CD3 antibody.
A thymic epithelial cell line (TEC1-4) established from newborn mouse thymus produced a cofactor to promote proliferation of… 
1990
1990
Ca2+ entry in T cells is activated by emptying the inositol 1,4,5-triphosphate sensitive Ca2+ pool.
1989
1989
Bivalent binding of an anti-CD3 antibody to Jurkat cells induces association of the T cell receptor complex with the cytoskeleton.
Ligand binding and cross-linking of TCR/CD3 complex leads to T cell stimulation in immunologic responses. As a prelude to… 
Highly Cited
1989
Highly Cited
1989
Requirement for delivery of signals by physical interaction and soluble factors from accessory cells in the induction of receptor-mediated T cell proliferation. Effectiveness of IFN-gamma modulation…
We analyzed the mechanism by which accessory cells support the induction of the proliferation of human peripheral blood T cells… 
1989
1989
T-cell activation. I. Evidence for a functional linkage between class I MHC antigens and the Tc-Ti complex.
This paper examines the possibility of a functional linkage between class I MHC molecules and the T-cell receptor complex for… 
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