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Muromonab-CD3

Known as: Anti-CD3 monoclonal antibody OKT 3, Anti-CD3 monoclonal antibody OKT3, Anti-CD3 
A murine IgG2a monoclonal antibody with immunosuppressive activity. Muromonab-CD3 binds to and inhibits CD3 on the surface of circulating T… Expand
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cytotoxic T lymphocytes (CTLs) directed to nonviral tumor–associated antigens do not survive long term and have limited antitumor… Expand
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Highly Cited
2004
Highly Cited
2004
  • G. Opelz, B. Döhler
  • American journal of transplantation : official…
  • 2004
  • Corpus ID: 11215482
We used the Collaborative Transplant Study database to analyze the incidence, risk, and impact of malignant lymphomas in… Expand
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Highly Cited
2001
Highly Cited
2001
Immunosuppression may contribute to the progression of cancer. In this study we assessed the structural and functional status of… Expand
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Highly Cited
1996
Highly Cited
1996
A mAb J43 has been produced against the product of the mouse PD-1 gene, a member of the Ig gene superfamily, which was previously… Expand
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Highly Cited
1994
Highly Cited
1994
Injection of anti-CD3 antibodies causes prompt expression of interleukin (IL)-4, IL-2, and interferon gamma (IFN-gamma) mRNA… Expand
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Highly Cited
1992
Highly Cited
1992
The classical type of programmed cell death is characterized by its dependence on de novo RNA and protein synthesis and… Expand
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Highly Cited
1990
Highly Cited
1990
BACKGROUND A sudden increase in the incidence of post-transplantation lymphoproliferative disorder among the patients in our… Expand
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Highly Cited
1990
Highly Cited
1990
Functional studies demonstrate that T cell activation often requires not only occupancy of the TCR but costimulatory interactions… Expand
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Highly Cited
1989
Highly Cited
1989
We studied the effects of cytomegalovirus (CMV) infection on 301 cardiac transplant recipients who were treated during the… Expand
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Highly Cited
1979
Highly Cited
1979
Three novel nonoclonal antibodies (designed OKT1, OKT3, and OKT4) were generated against surface determinants of human peripheral… Expand
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