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Muromonab-CD3

Known as: Anti-CD3 monoclonal antibody OKT 3, Anti-CD3 monoclonal antibody OKT3, Anti-CD3 
A murine IgG2a monoclonal antibody with immunosuppressive activity. Muromonab-CD3 binds to and inhibits CD3 on the surface of circulating T… 
National Institutes of Health

Related topics

Related topics

17 relations
CD3 AntigensDecreased Immunologic Activity [PE]Drug AllergyEdema

Broader (2)

Immunologic FactorsImmunosuppressive Agents

Narrower (2)

OrthoclonehOKT3 gamma4

Papers overview

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1999
1999
A humanized anti-CD3 antibody, HuM291, with low mitogenic activity, mediates complete and reversible T-cell depletion in chimpanzees.
BACKGROUND An anti-CD3 antibody that reduces cytokine release syndrome (CRS) while maintaining immunosuppression would be a major… 
1996
1996
A randomized trial comparing safety and efficacy of OKT3 and a monoclonal anti-interleukin-2 receptor antibody (BT563) in the prevention of acute rejection after heart transplantation.
In a prospective randomized trial, BT563, a murine IgG, anti-interleukin-2 receptor antibody, was compared with OKT3 for use as… 
1993
1993
Thirty-year trends in clinical kidney transplantation.
Trends in one-year graft survival rates seen in the past 30 years were examined in the UCLA and UNOS Registries. Some of the… 
1986
1986
Serial changes in cellular immunity of septic patients with multiple organ‐system failure
Total lymphocyte count, lymphocyte cell-surface markers (OKT3, OKT4, OKT8, and B-1), serum complement factors (C3 and C4… 
1985
1985
In vitro maturation of B cells in chronic lymphocytic leukemia. I. Synergistic action of phorbol ester and interleukin 2 in the induction of Tac antigen expression and interleukin 2 responsiveness in…
Recent evidence indicates that interleukin 2 (IL 2), formerly thought to serve as growth factor exclusively for activated T cells… 
1985
1985
Subsets of human large granular lymphocytes (LGL) exhibit accessory cell functions.
The present study shows that human large granular lymphocytes (LGL) depleted of OKT3 (T lymphocytes) and Leu-M1-positive… 
1984
1984
Identity of immune cells in graft-versus-host disease of the skin. Analysis using monoclonal antibodies by indirect immunofluorescence.
The cellular infiltrate in skin biopsies of 9 patients with graft-versus-host disease (GVHD) has been characterized with the use… 
1983
1983
B cell activity in systemic lupus erythematosus: depressed in vivo humoral immune response to a primary antigen (haemocyanin) and increased in vitro spontaneous immunoglobulin synthesis.
B lymphocyte studies, in vivo and in vitro, were performed in 28 patients with systemic lupus erythematosus (SLE). After… 
1982
1982
Characterization of immunoregulatory T cells during pregnancy by monoclonal antibodies.
T Lymphocyte subpopulations were characterized by means of monoclonal antibodies in 44 pregnant women at different stages of… 
1982
1982
In vitro mixed skin cell lymphocyte culture reaction (MSLR) in man: analysis of the epidermal cell and T cell subpopulations.
The nature of normal human epidermal cells (EC) and peripheral blood (PB) cells that react in vitro in allogeneic mixed skin cell…