Muromonab-CD3

Known as: Anti-CD3 monoclonal antibody OKT 3, Anti-CD3 monoclonal antibody OKT3, Anti-CD3 
A murine IgG2a monoclonal antibody with immunosuppressive activity. Muromonab-CD3 binds to and inhibits CD3 on the surface of circulating T… (More)
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
Cytotoxic T lymphocytes (CTLs) directed to nonviral tumor–associated antigens do not survive long term and have limited antitumor… (More)
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Highly Cited
2007
Highly Cited
2007
Epstein-Barr virus-induced gene 3 (EBI3) and the p35 subunit of IL-12 have been reported to form a heterodimeric hematopoietin in… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Type 1 diabetes mellitus is a chronic autoimmune disease caused by the pathogenic action of T lymphocytes on insulin… (More)
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Highly Cited
2001
Highly Cited
2001
Immunosuppression may contribute to the progression of cancer. In this study we assessed the structural and functional status of… (More)
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Highly Cited
1996
Highly Cited
1996
A mAb J43 has been produced against the product of the mouse PD-1 gene, a member of the Ig gene superfamily, which was previously… (More)
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Highly Cited
1996
Highly Cited
1996
Human CD4+ T cells, activated by allogeneic monocytes in a primary mixed lymphocyte reaction in the presence of exogenous… (More)
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Highly Cited
1994
Highly Cited
1994
Anti-CD3 monoclonal antibodies suppress immune responses by transient T-cell depletion and antigenic modulation of the CD3/T-cell… (More)
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Highly Cited
1994
Highly Cited
1994
Injection of anti-CD3 antibodies causes prompt expression of interleukin (IL)-4, IL-2, and interferon gamma (IFN-gamma) mRNA… (More)
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Highly Cited
1992
Highly Cited
1992
The classical type of programmed cell death is characterized by its dependence on de novo RNA and protein synthesis and… (More)
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Highly Cited
1989
Highly Cited
1989
We studied the effects of cytomegalovirus (CMV) infection on 301 cardiac transplant recipients who were treated during the… (More)
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