ubenimex

Known as: L-Leucine, N-(3-amino-2-hydroxy-1-oxo-4-phenylbutyl)-, [S-(R*,S*)]-, N-[(2S,3R)-4-phenyl-3-amino-2-hydroxybutyryl]-L-leucine, (3-amino-2-hydroxy-4-phenylbutanoyl)-L-leucine 
A microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Ubenimex competitively inhibits many aminopeptidases… (More)
National Institutes of Health

Papers overview

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Highly Cited
2004
Highly Cited
2004
The degradation of cellular proteins by proteasomes generates peptides 2-24 residues long, which are hydrolyzed rapidly to amino… (More)
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Highly Cited
2003
Highly Cited
2003
Carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyric acid-L-histidine) are two naturally occurring… (More)
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Highly Cited
2002
Highly Cited
2002
Polar transport of the plant hormone auxin is regulated at the cellular level by inhibition of efflux from a plasma membrane (PM… (More)
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Highly Cited
2002
Highly Cited
2002
Lethal toxin is a major anthrax virulence factor, causing the rapid death of experimental animals. Lethal toxin can enter most… (More)
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Highly Cited
2000
Highly Cited
2000
 The 1-N-naphthylphthalamic acid (NPA)-binding protein is a putative negative regulator of polar auxin transport that has been… (More)
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Review
2000
Review
2000
The removal of the N-terminal methionine from proteins and peptides is dependent upon a novel class of proteases typified by the… (More)
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Highly Cited
1998
Highly Cited
1998
Most antigenic peptides presented on major histocompatibility complex class I molecules are generated during protein breakdown by… (More)
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Highly Cited
1994
Highly Cited
1994
Comparison of the anthrax toxin lethal factor (LF) amino acid sequence with sequences in the Swiss protein database revealed… (More)
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Review
1993
Review
1993
Aminopeptidases catalyze the cleavage of amino acids from the amino terminus of protein or peptide substrates. They are widely… (More)
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Highly Cited
1987
Highly Cited
1987
High performance liquid chromatography studies documented the presence of an enzyme activity, N-acetylated alpha-linked acidic… (More)
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