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tyrosine 3-monooxygenase activity

Known as: L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating), tyrosine hydroxylase activity, tyrosine 3-hydroxylase activity 
Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O. [EC:1.14… 
National Institutes of Health

Related topics

Related topics

4 relations
TH geneTyrosine 3-Monooxygenasenegative regulation of tyrosine 3-monooxygenase activitypositive regulation of tyrosine 3-monooxygenase activity

Papers overview

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Highly Cited
1980
Highly Cited
1980
Long-term effects of multiple doses of methamphetamine on tryptophan hydroxylase and tyrosine hydroxylase activity in rat brain.
Tryptophan hydroxylase (TPH) activity was measured in various rat brain regions after administering large doses of… 
Highly Cited
1978
Highly Cited
1978
Light stimulates tyrosine hydroxylase activity and dopamine synthesis in retinal amacrine neurons.
Retinal dopamine-containing amacrine neurons are rapidly activated by light, as shown by an increase in the rate of dopamine… 
Highly Cited
1978
Highly Cited
1978
Long-term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration.
Silicone pellets containing d-amphetamine base were implanted subcutaneously in rats. These pellets release amphetamine… 
Highly Cited
1975
Highly Cited
1975
The pharmacological and anatomical substrates of the amphetamine response in the rat
Highly Cited
1975
Highly Cited
1975
Effects of Chronic Exposure to Stressors on Avoidance‐Escape Behavior and on Brain Norepinephrine*
&NA; A single exposure to a severe stressor (either cold swim or inescapable shock) impairs subsequent performance in a shuttle… 
Highly Cited
1972
Highly Cited
1972
Evidence for a receptor‐mediated feedback control of striatal tyrosine hydroxylase activity
WE have previously reported that cutting the nigrostriatal dopamine-carrying axons unexpectedly results in a transient increase… 
Highly Cited
1971
Highly Cited
1971
Depletion of brain noradrenaline and dopamine by 6‐hydroxydopamine
1 After intracisternal administration, 6‐hydroxydopamine had a greater effect on brain noradrenaline than on dopamine. 2… 
Highly Cited
1969
Highly Cited
1969
Increase in tyrosine hydroxylase activity after reserpine administration.
After the administration of reserpine, the in vitro tyrosine hydroxylase activity increases in rat, guinea-pig, mouse and rabbit… 
Highly Cited
1969
Highly Cited
1969
In vitro differentiation of a mouse neuroblastoma.
Mouse tumor C1300 has been established in tissue culture. The cells have a round cell morphology in both the subcutaneous tumor… 
Highly Cited
1966
Highly Cited
1966
The tyrosine hydroxylase activity of mammalian tyrosinase.
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