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tyrosine 3-monooxygenase activity

Known as: L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating), tyrosine hydroxylase activity, tyrosine 3-hydroxylase activity 
Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O. [EC:1.14… 
National Institutes of Health

Related topics

Related topics

4 relations
TH geneTyrosine 3-Monooxygenasenegative regulation of tyrosine 3-monooxygenase activitypositive regulation of tyrosine 3-monooxygenase activity

Papers overview

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Highly Cited
1988
Highly Cited
1988
Evidence that adenosine A2 and dopamine autoreceptors antagonistically regulate tyrosine hydroxylase activity in rat striatal synaptosomes
Highly Cited
1981
Highly Cited
1981
Short and long term changes in tyrosine hydroxylase activity in rat brain after subtotal destruction of central noradrenergic neurons
The administration of 6-hydroxydopamine into the cerebroventricles of the rat produced a rapid and permanent decrease of… 
Highly Cited
1980
Highly Cited
1980
Compensatory increase in tyrosine hydroxylase activity in rat brain after intraventricular injections of 6-hydroxydopamine.
The neurotoxin 6-hydroxydopamine produced a permanent loss of endogenous norepinephrine and of 3H-labeled norepinephrine uptake… 
Highly Cited
1980
Highly Cited
1980
Effects of Catechol Estrogens1 and Catecholamines on Hypothalamic and Corpus Striatal Tyrosine Hydroxylase Activity
Abstract: The effects of catechol estrogens on tyrosine hydroxylase activity in hypothalamic and corpus striatal extracts were… 
Highly Cited
1979
Highly Cited
1979
THE EFFECTS OF CHRONIC REGIMENS OF CLORGYLINE AND PARGYLINE ON MONOAMINE METABOLISM IN THE RAT BRAIN
The effects of chronic administration of clorgyline and pargyline on rat brain monoamine metabolism have been examined. The… 
Highly Cited
1979
Highly Cited
1979
Dissociation between the presynaptic dopamine-sensitive adenylate cyclase and [3H]spiperone binding sites in rat substantia nigra
Highly Cited
1978
Highly Cited
1978
Direct inhibition of tyrosine hydroxylase activity by catechol estrogens.
Highly Cited
1977
Highly Cited
1977
Effect of 17 ß-estradiol on hypothalamic tyrosine hydroxylase activity
Highly Cited
1975
Highly Cited
1975
Effects of stress on catecholamines and tyrosine hydroxylase activity of individual hypothalamic nuclei.
The effects of acute stress on norepinephrine (NE) and dopamine (DA) concentrations and of repeated stress on tyrosine… 
Highly Cited
1975
Highly Cited
1975
Role of cyclic amp in differentiation of human neuroblastoma cells in culture
The inhibitors of cyclic AMP phosphodiesterase (papaverine and 4‐(‐3‐butoxy‐4‐methoxybenzyl)‐2‐imidazolidinone), serum‐free… 
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