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tyrosine 3-monooxygenase activity
Known as:
L-tyrosine,tetrahydrobiopterin:oxygen oxidoreductase (3-hydroxylating)
, tyrosine hydroxylase activity
, tyrosine 3-hydroxylase activity
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Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O. [EC:1.14…
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National Institutes of Health
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Related topics
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4 relations
TH gene
Tyrosine 3-Monooxygenase
negative regulation of tyrosine 3-monooxygenase activity
positive regulation of tyrosine 3-monooxygenase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1988
Highly Cited
1988
Evidence that adenosine A2 and dopamine autoreceptors antagonistically regulate tyrosine hydroxylase activity in rat striatal synaptosomes
P. Onali
,
M. Olianas
,
Bert Bunse
Brain Research
1988
Corpus ID: 22425879
Highly Cited
1981
Highly Cited
1981
Short and long term changes in tyrosine hydroxylase activity in rat brain after subtotal destruction of central noradrenergic neurons
A. Acheson
,
M. Zigmond
Journal of Neuroscience
1981
Corpus ID: 207510313
The administration of 6-hydroxydopamine into the cerebroventricles of the rat produced a rapid and permanent decrease of…
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Highly Cited
1980
Highly Cited
1980
Compensatory increase in tyrosine hydroxylase activity in rat brain after intraventricular injections of 6-hydroxydopamine.
A. Acheson
,
M. Zigmond
,
E. Stricker
Science
1980
Corpus ID: 43798126
The neurotoxin 6-hydroxydopamine produced a permanent loss of endogenous norepinephrine and of 3H-labeled norepinephrine uptake…
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Highly Cited
1980
Highly Cited
1980
Effects of Catechol Estrogens1 and Catecholamines on Hypothalamic and Corpus Striatal Tyrosine Hydroxylase Activity
M. Foreman
,
J. C. Porter
Journal of Neurochemistry
1980
Corpus ID: 30080762
Abstract: The effects of catechol estrogens on tyrosine hydroxylase activity in hypothalamic and corpus striatal extracts were…
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Highly Cited
1979
Highly Cited
1979
THE EFFECTS OF CHRONIC REGIMENS OF CLORGYLINE AND PARGYLINE ON MONOAMINE METABOLISM IN THE RAT BRAIN
I. C. Campbell
,
D. Robinson
,
W. Lovenberg
,
D. Murphy
Journal of Neurochemistry
1979
Corpus ID: 50003
The effects of chronic administration of clorgyline and pargyline on rat brain monoamine metabolism have been examined. The…
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Highly Cited
1979
Highly Cited
1979
Dissociation between the presynaptic dopamine-sensitive adenylate cyclase and [3H]spiperone binding sites in rat substantia nigra
M. Quik
,
P. Emson
,
Eileen M. Joyce
Brain Research
1979
Corpus ID: 22970973
Highly Cited
1978
Highly Cited
1978
Direct inhibition of tyrosine hydroxylase activity by catechol estrogens.
T. Lloyd
,
J. Weisz
Journal of Biological Chemistry
1978
Corpus ID: 2298124
Highly Cited
1977
Highly Cited
1977
Effect of 17 ß-estradiol on hypothalamic tyrosine hydroxylase activity
V. Luine
,
B. McEwen
,
I. Black
Brain Research
1977
Corpus ID: 53162354
Highly Cited
1975
Highly Cited
1975
Effects of stress on catecholamines and tyrosine hydroxylase activity of individual hypothalamic nuclei.
M. Palkovits
,
R. M. Kobayashi
,
J. Kizer
,
D. Jacobowitz
,
I. Kopin
Neuroendocrinology
1975
Corpus ID: 46811420
The effects of acute stress on norepinephrine (NE) and dopamine (DA) concentrations and of repeated stress on tyrosine…
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Highly Cited
1975
Highly Cited
1975
Role of cyclic amp in differentiation of human neuroblastoma cells in culture
K. Prasad
,
Surendra Kumar
Cancer
1975
Corpus ID: 5619547
The inhibitors of cyclic AMP phosphodiesterase (papaverine and 4‐(‐3‐butoxy‐4‐methoxybenzyl)‐2‐imidazolidinone), serum‐free…
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