TH gene

Known as: TH, Tyrosine Hydroxylase Gene, DYT5b 
This gene plays a role in dopamine biosynthesis.

Topic mentions per year

Topic mentions per year

1964-2018
010020030019642018

Papers overview

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Highly Cited
2013
Highly Cited
2013
The pace of nigrostriatal degeneration, both with regards to striatal denervation and loss of melanin and tyrosine hydroxylase… (More)
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Highly Cited
2003
Highly Cited
2003
Dopamine (DA) is the only catecholaminergic neurotransmitter in the fruit fly Drosophila melanogaster. Dopaminergic neurons have… (More)
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Highly Cited
2002
Highly Cited
2002
The alpha-synuclein gene is implicated in the pathogenesis of Parkinson's disease. Although alpha-synuclein function is uncertain… (More)
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Highly Cited
1999
Highly Cited
1999
OBJECTIVE Abnormalities in dopamine neurotransmission in the prefrontal cortex have been implicated in the pathophysiology of… (More)
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Highly Cited
1998
Highly Cited
1998
Interactions between dopamine and glutamate play prominent roles in memory, addiction, and schizophrenia. Several lines of… (More)
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Highly Cited
1996
Highly Cited
1996
We have examined the biochemical and histological effects of high concentrations of dopamine (0.05-1.0 micromol) injected into… (More)
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Highly Cited
1994
Highly Cited
1994
Adeno-associated viral (AAV) vectors are non-pathogenic, integrating DNA vectors in which all viral genes are removed and helper… (More)
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Highly Cited
1992
Highly Cited
1992
Physiological and pharmacological studies indicate that descending projections from the prefrontal cortex modulate dopaminergic… (More)
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Highly Cited
1987
Highly Cited
1987
Mesostriatal projections, which arise from dopaminergic and non-dopaminergic neurons in the ventral tegmental area, substantia… (More)
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Highly Cited
1984
Highly Cited
1984
Tyrosine hydroxylase-immunoreactive fibres in the rat neostriatum were studied in the electron microscope in order to determine… (More)
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