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TH gene

Known as: TH, Tyrosine Hydroxylase Gene, DYT5b 
This gene plays a role in dopamine biosynthesis.
National Institutes of Health

Related topics

Related topics

8 relations
AnabolismBiogenic Amine Metabolic ProcessOxidation-ReductionSynaptic Transmission

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2004
Review
2004
Novel therapeutic effects of the anti-convulsant, zonisamide, on Parkinson's disease.
We found that zonisamide (ZNS) has beneficial effects on Parkinson's disease (PD). ZNS is originally synthesized in Japan and has… 
Highly Cited
1994
Highly Cited
1994
CNS monoamine cell groups projecting to pancreatic vagal motor neurons: a transneuronal labeling study using pseudorabies virus
Highly Cited
1992
Highly Cited
1992
Behavioural analysis of unilateral monoamine depletion in the marmoset.
Unilateral stereotaxic injections of 6-hydroxydopamine (6-OHDA) into the nigrostriatal bundle of marmosets (Callithrix jacchus… 
Highly Cited
1989
Highly Cited
1989
Ontogeny of dopaminergic D-2 receptors in the rat nervous system: Characterization and detailed autoradiographic mapping with [125I]iodosulpride
Highly Cited
1989
Highly Cited
1989
Immunocytochemical and physiological evidence of a synapse between dopamine- and luteinizing hormone releasing hormone-containing neurons in the ewe median eminence.
Immunocytochemical labeling revealed that the arcuate nucleus (ARN) of the ewe's hypothalamus contains numerous tyrosine… 
Highly Cited
1989
Highly Cited
1989
Molecular cloning and sequencing of a cDNA of rat dopa decarboxylase: partial amino acid homologies with other enzymes synthesizing catecholamines.
Dopa decarboxylase (DDC; aromatic-L-amino-acid decarboxylase; aromatic-L-amino-acid carboxylase, EC 4.1.1.28) was purified from… 
Highly Cited
1975
Highly Cited
1975
SELECTIVE INCREASE OF BRAIN DOPAMINE SYNTHESIS BY SULPIRIDE
—Sulpiride (5–200 mg/kg) increases brain HVA and DOPAC levels, causes no change in dopamine concentration, does not interfere… 
Highly Cited
1974
Highly Cited
1974
The effect of endocrinological manipulations on tyrosine hydroxylase and dopamine-beta-hydroxylase activities in individual hypothalamic nuclei of the adult male rat.
Using a recently developed microdissection method, individual hypothalamic nuclei were removed from the brains of adult male rats… 
Highly Cited
1973
Highly Cited
1973
Effect of prostaglandin E 2 on central and peripheral catecholamine neurons.
Highly Cited
1968
Highly Cited
1968
Tissue fractionation and catecholamines. II. Intracellular distribution patterns of tyrosine hydroxylase, dopa decarboxylase, dopamine-beta-hydroxylase, phenylethanolamine N-methyltransferase and…
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