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[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role.
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Receptor-binding properties in vitro and in vivo of ritanserin: A very potent and long acting serotonin-S2 antagonist.
TLDR
In vivo binding assays using [3H]spiperone confirmed the occupation of frontal cortical serotonin-S2 sites following low dosage of ritanserin and a minor occupation of striatal dopamine-D2 sites.
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Receptor binding profile of R 41 468, a novel antagonist at 5-HT2 receptors.
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Pharmacological properties of a potent and selective nonpeptide substance P antagonist.
TLDR
RP 67580, a SP antagonist, belongs to a class of drugs that may be useful in the management of various clinical pathologies where pain and neurogenic inflammation are involved and was of the same order as that of morphine.
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Serotonergic component of neuroleptic receptors
TLDR
It is suggested that serotonergic, as well as dopamine agonists or antagonists for rat frontal cortex and striatal receptors are involved in the mechanism of action of neuroleptic drugs.
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Two populations of neurotensin binding sites in murine brain: discrimination by the antihistamine levocabastine reveals markedly different radioautographic distribution.
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Different postnatal ontogeny of two [3H]neurotensin binding sites in rat brain
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Spiperone: a ligand of choice for neuroleptic receptors. 3. Subcellular distribution of neuroleptic drugs and their receptors in various rat brain areas.
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Different Subcellular Localization of Neurotensin‐Receptor and Neurotensin‐Acceptor Sites in the Rat Brain Dopaminergic System
TLDR
NT2 sites are probably associated with presynaptic nigrostriatal dopaminergic terminals in the caudate‐putamen but not in the nucleus accumbens and the olfactory tubercle, and a possible association of NT1 sites with glial cells is suggested.
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Axoplasmic transport of muscarinic receptors
TLDR
This work provides direct biochemical evidence for the occurrence in dog splenic nerve of muscarinic receptors which seem to move along the axon as suggested by their rapid accumulation on either side of a ligature.
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