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Tyrosine 3-Monooxygenase
Known as:
Tyrosine 3-Monooxygenase [Chemical/Ingredient]
, hydroxylase tyrosine
, Tyrosine Hydroxylase
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An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water…
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National Institutes of Health
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Related topics
Related topics
13 relations
In Blood
Process of secretion
TH gene
Tyrosine
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Broader (2)
Mixed Function Oxygenases
Oxygenases
Narrower (1)
Tyrosine 3-Monooxygenase, human
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration
L. Qin
,
Xuefei Wu
,
+5 authors
F. Crews
Glia
2007
Corpus ID: 40951364
Inflammation is implicated in the progressive nature of neurodegenerative diseases, such as Parkinson's disease, but the…
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Highly Cited
2006
Highly Cited
2006
Expression of ghrelin receptor mRNA in the rat and the mouse brain
J. Zigman
,
Juli E. Jones
,
Charlotte E. Lee
,
C. Saper
,
J. Elmquist
The Journal of comparative neurology
2006
Corpus ID: 40585256
Ghrelin is a hormone that stimulates growth hormone secretion and signals energy insufficiency via interaction with its receptor…
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Highly Cited
2000
Highly Cited
2000
Projections from the Rat Prefrontal Cortex to the Ventral Tegmental Area: Target Specificity in the Synaptic Associations with Mesoaccumbens and Mesocortical Neurons
David B. Carr
,
S. Sesack
Journal of Neuroscience
2000
Corpus ID: 15909830
Excitatory projections from the prefrontal cortex (PFC) to the ventral tegmental area (VTA) play an important role in regulating…
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Review
1996
Review
1996
Antidepressants and hypothalamic-pituitary-adrenocortical regulation.
Florian Holsboer
,
N. Barden
Endocrine reviews
1996
Corpus ID: 43168522
I. Introduction PAST studies of antidepressants have focused almost exclusively on their effects on the metabolism and receptors…
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Highly Cited
1994
Highly Cited
1994
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brain
M. Kaplitt
,
P. Leone
,
+4 authors
M. During
Nature Genetics
1994
Corpus ID: 35218533
Adeno-associated viral (AAV) vectors are non-pathogenic, integrating DNA vectors in which all viral genes are removed and helper…
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Highly Cited
1986
Highly Cited
1986
Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.
M. Montminy
,
K. Sevarino
,
John A. Wagner
,
G. Mandel
,
R. Goodman
Proceedings of the National Academy of Sciences…
1986
Corpus ID: 19960486
We have examined the regulation of somatostatin gene expression by cAMP in PC12 rat pheochromocytoma cells transfected with the…
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Highly Cited
1983
Highly Cited
1983
The Rat Brain in Stereotaxic Coordinates
G. Paxinos
,
Charles Watson
1983
Corpus ID: 86211914
Highly Cited
1983
Highly Cited
1983
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons—1. Identification and characterization
A. Grace
,
B. Bunney
Neuroscience
1983
Corpus ID: 25412317
Highly Cited
1970
Highly Cited
1970
Receptor activity and turnover of dopamine and noradrenaline after neuroleptics.
N. Andén
,
Sherrel G. Butcher
,
H. Corrodi
,
K. Fuxe
,
Urban Ungerstedt
European Journal of Pharmacology
1970
Corpus ID: 4610583
Highly Cited
1964
Highly Cited
1964
TYROSINE HYDROXYLASE. THE INITIAL STEP IN NOREPINEPHRINE BIOSYNTHESIS.
T. Nagatsu
,
M. Levitt
,
S. Udenfriend
Journal of Biological Chemistry
1964
Corpus ID: 6680748
After demonstration of the decarboxylation of 3,4-dihydroxyphenylalanine (dopa)’ to dopamine (I), the pathway for biosynthesis of…
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