Tyrosine 3-Monooxygenase

Known as: Tyrosine 3-Monooxygenase [Chemical/Ingredient], hydroxylase tyrosine, Tyrosine Hydroxylase 
An enzyme that catalyzes the conversion of L-tyrosine, tetrahydrobiopterin, and oxygen to 3,4-dihydroxy-L-phenylalanine, dihydrobiopterin, and water… (More)

Topic mentions per year

Topic mentions per year

1964-2018
0204019642018

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Adult rat-derived hippocampal progenitor cells express many of the molecules implicated in midbrain dopaminergic determination… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
To identify specific genes affecting vulnerability or resistance, we performed a whole-autosomal genome scan for genetic linkage… (More)
  • table I
  • table II
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The decrement in dopamine levels exceeds the loss of dopaminergic neurons in Parkinson's disease (PD) patients and experimental… (More)
  • figure 2
  • figure 1
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
The polymorphic HUMTH01 microsatellite, located in the first intron of the tyrosine hydroxylase gene is characterized by a… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Tyrosine hydroxylase catalyses the initial, rate-limiting step in the catecholamine biosynthetic pathway. Catecholamines, which… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
We studied levels of tyrosine hydroxylase immunoreactivity and phosphorylation state in the ventral tegmental area (VTA) and… (More)
Is this relevant?
Highly Cited
1990
Highly Cited
1990
The site specificity of tyrosine hydroxylase phosphorylation in intact PC12 cells, labeled with 32Pi, was investigated. Digestion… (More)
  • figure 2
  • figure 3
  • table I
  • figure 5
  • table II
Is this relevant?
Highly Cited
1980
Highly Cited
1980
Tryptophan hydroxylase (TPH) activity was measured in various rat brain regions after administering large doses of… (More)
Is this relevant?
Highly Cited
1965
Highly Cited
1964
Highly Cited
1964
After demonstration of the decarboxylation of 3,4-dihydroxyphenylalanine (dopa)’ to dopamine (I), the pathway for biosynthesis of… (More)
  • figure 1
  • table II
  • table III
  • table IV
  • figure 2
Is this relevant?