tianeptine

Known as: (3-chloro-6-methyl-5,5-dioxo-6,11-dihydrodibenzo(c,f)(1,2)thiazepin-11-yl)-7-aminoheptanoic acid 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2018
010203019862018

Papers overview

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Highly Cited
2004
Highly Cited
2004
BACKGROUND Selective serotonin reuptake inhibitors (SSRIs) are efficacious in the treatment of a variety of fear or anxiety… (More)
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Highly Cited
2004
Highly Cited
2004
Excitatory amino acids play a key role in stress-induced remodeling of dendrites in the hippocampus as well as in suppression of… (More)
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Highly Cited
2004
Highly Cited
2004
BACKGROUND Recent clinical and preclinical studies suggest that major depression may be related to impairments of structural… (More)
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Highly Cited
2002
Highly Cited
2002
Recent hypotheses on the action of antidepressants imply a modulation of excitatory amino acid transmission. Here, the effects of… (More)
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Highly Cited
2001
Highly Cited
2001
Stress-induced structural remodeling in the adult hippocampus, involving debranching and shortening of dendrites and suppression… (More)
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Highly Cited
1999
Highly Cited
1999
This study investigated whether 21 days of restraint stress (6 hr/day) and the subsequent hippocampal dendritic atrophy would… (More)
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Highly Cited
1996
Highly Cited
1996
Chronic restraint stress causes significant dendritic atrophy of CA3 pyramidal neurons that reverts to baseline within a week… (More)
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Highly Cited
1994
Highly Cited
1994
Restraint stress, 6 h/day for 21 days, caused an impairment, during acquisition, of the performance of a spatial memory task, the… (More)
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Highly Cited
1992
Highly Cited
1992
Repeated 6-h daily restraint stress over 21 days reduces length and number of branch points of hippocampal CA3c pyramidal… (More)
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1987
1987
Tianeptine is a tricyclic agent provided with antidepressant activity in experimental models and in clinical trials. In vitro… (More)
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