S. Kennedy

Publications625
h-index95
Citations35,716
Highly Influential Citations1,335
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Deep Brain Stimulation for Treatment-Resistant Depression
TLDR
It is suggested that disrupting focal pathological activity in limbic-cortical circuits using electrical stimulation of the subgenual cingulate white matter can effectively reverse symptoms in otherwise treatment-resistant depression. Expand
Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy.
TLDR
Brain changes underlying response to CBT were examined using resting-state fluorine-18-labeled deoxyglucose positron emission tomography to examine changes associated with cognitive behavior therapy (CBT). Expand
Subcallosal Cingulate Gyrus Deep Brain Stimulation for Treatment-Resistant Depression
TLDR
This study suggests that DBS is relatively safe and provides significant improvement in patients with TRD and likely acts by modulating brain networks whose dysfunction leads to depression. Expand
Bulimia nervosa in a Canadian community sample: prevalence and comparison of subgroups.
TLDR
This study confirms other prevalence estimates of bulimia nervosa and its comorbid diagnoses from studies that were based on sound methodologies and points to the arbitrary aspects of the frequency of binge eating as a diagnostic threshold criterion for the disorder. Expand
Limbic–frontal circuitry in major depression: a path modeling metanalysis
TLDR
The creation of such models is a first step toward full characterization of the depression phenotype at the neural systems level, with implications for the future development of brain-based algorithms to determine optimal treatment selection for individual patients. Expand
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar…
The Canadian Network for Mood and Anxiety Treatments published guidelines for the management of bipolar disorder in 2005, with updates in 2007 and 2009. This third update, in conjunction with the… Expand
Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression.
TLDR
The results of the present study provide further support for a dysfunction in cortical-limbic circuitry in depression, which is at least partly reversed after successful paroxetine treatment. Expand
Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) collaborative update of CANMAT guidelines for the management of patients with bipolar…
The Canadian Network for Mood and Anxiety Treatments (CANMAT) published guidelines for the management of bipolar disorder in 2005, with a 2007 update. This second update, in conjunction with the… Expand
Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 Clinical Guidelines for the Management of Adults with Major Depressive Disorder
TLDR
Despite the limited evidence base, extant data and clinical experience suggest that each of these special populations can benefit from the systematic application of treatment guidelines for treatment of MDD. Expand
Comparisons of men with full or partial eating disorders, men without eating disorders, and women with eating disorders in the community.
TLDR
Men with eating disorders showed higher rates of psychiatric comorbidity and more psychosocial morbidity than men without eating disorders and both groups suffer similar psychossocial morbidity. Expand
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