Neurobiological and Clinical Effects of the Antidepressant Tianeptine

@article{Kasper2008NeurobiologicalAC,
  title={Neurobiological and Clinical Effects of the Antidepressant Tianeptine},
  author={S. Kasper and B. McEwen},
  journal={CNS Drugs},
  year={2008},
  volume={22},
  pages={15-26}
}
The precise neurobiological processes involved in depression are not clear, but it is recognized that numerous factors are involved, including changes in neurotransmitter systems and brain plasticity. Neuroplasticity refers to the ability of the brain to adapt functionally and structurally to stimuli. Impairment of neuroplasticity in the hippocampus, amygdala and cortex is hypothesized to be the mechanism by which cognitive function, learning, memory and emotions are altered in depression. The… Expand
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References

SHOWING 1-10 OF 126 REFERENCES
Molecular mechanisms of neuroplasticity and pharmacological implications: the example of tianeptine
  • 159
A Neurotrophic Model for Stress-Related Mood Disorders
  • 2,678
  • Highly Influential
Regulation of Cellular Plasticity Cascades in the Pathophysiology and Treatment of Mood Disorders
  • 177
Preclinical research on stress, memory, and the brain in the development of pharmacotherapy for depression
  • 76
Neurobiology of mood, anxiety, and emotions as revealed by studies of a unique antidepressant: tianeptine
  • 124
  • PDF
Antidepressant treatment with tianeptine reduces apoptosis in the hippocampal dentate gyrus and temporal cortex
  • 184
Hippocampal Neurogenesis, Depressive Disorders, and Antidepressant Therapy
  • 71
  • Highly Influential
  • PDF
Neuroimaging studies of mood disorders
  • W. Drevets
  • Psychology, Medicine
  • Biological Psychiatry
  • 2000
  • 1,249
  • PDF
Stress-induced changes in cerebral metabolites, hippocampal volume, and cell proliferation are prevented by antidepressant treatment with tianeptine
  • 1,037
  • Highly Influential
  • PDF
Neural plasticity: consequences of stress and actions of antidepressant treatment
  • R. Duman
  • Medicine, Biology
  • Dialogues in clinical neuroscience
  • 2004
  • 71
  • Highly Influential
  • PDF
...
1
2
3
4
5
...