Neurobiological and Clinical Effects of the Antidepressant Tianeptine
@article{Kasper2008NeurobiologicalAC, title={Neurobiological and Clinical Effects of the Antidepressant Tianeptine}, author={Siegfried Kasper and Bruce S. McEwen}, journal={CNS Drugs}, year={2008}, volume={22}, pages={15-26} }
The precise neurobiological processes involved in depression are not clear, but it is recognized that numerous factors are involved, including changes in neurotransmitter systems and brain plasticity. Neuroplasticity refers to the ability of the brain to adapt functionally and structurally to stimuli. Impairment of neuroplasticity in the hippocampus, amygdala and cortex is hypothesized to be the mechanism by which cognitive function, learning, memory and emotions are altered in depression. The…
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