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Emotion Circuits in the Brain
The field of neuroscience has, after a long period of looking the other way, again embraced emotion as an important research area. Much of the progress has come from studies of fear, and especiallyExpand
Emotion circuits in the brain.
  • Joseph E LeDoux
  • Psychology, Medicine
  • Annual review of neuroscience
  • 1 April 2009
TLDR
This work has pinpointed the amygdala as an important component of the system involved in the acquisition, storage, and expression of fear memory and has elucidated in detail how stimuli enter, travel through, and exit the amygdala. Expand
The emotional brain
What happens in our brains to make us feel fear, love, hate, anger, joy? Do we control our emotions, or do they control us? Do animals have emotions? How can traumatic experiences in early childhoodExpand
Differential contribution of amygdala and hippocampus to cued and contextual fear conditioning.
TLDR
An associative roles for the amygdala and a sensory relay role for the hippocampus are suggested in fear conditioning, which is involved in the conditioning of fear responses to simple, modality-specific conditioned stimuli as well as to complex, polymodal stimuli. Expand
Extinction Learning in Humans Role of the Amygdala and vmPFC
TLDR
The neural mechanisms of fear extinction in humans are explored and activation in the vmPFC was primarily linked to the expression of fear learning during a delayed test of extinction, indicating that the mechanisms of extinction learning may be preserved across species. Expand
Emotion: clues from the brain.
TLDR
The Neural Basis of Fear, Volitional Control of Emotion, and Psychopathological Issues are reviewed. Expand
Preventing the return of fear in humans using reconsolidation update mechanisms
TLDR
The adaptive role of reconsolidation as a window of opportunity to rewrite emotional memories is demonstrated, and a non-invasive technique that can be used safely in humans to prevent the return of fear is suggested. Expand
The Emotional Brain, Fear, and the Amygdala
  • Joseph E LeDoux
  • Psychology, Medicine
  • Cellular and Molecular Neurobiology
  • 1 October 2003
TLDR
Research on the role of the amygdala in fear conditioning, a behavioral procedure used to couple meaningless environmental stimuli to emotional (defense) response networks, concludes that the amygdala plays critical role in linking external stimuli to defense responses. Expand
Different projections of the central amygdaloid nucleus mediate autonomic and behavioral correlates of conditioned fear
TLDR
Electrolytic and ibotenic acid lesions of the LH demonstrate that neurons in the LH are involved in the autonomic, but not the behavioral, conditioned response pathway, whereas neurons inThe caudal CG are involvedIn the behavioral and autonomic pathway, although different efferent projections of the central amygdala thus appear to mediate the behavioraland autonomic concomitants of conditioned fear. Expand
The Emotional Brain: The Mysterious Underpinnings of Emotional Life
What happens in our brains to make us feel fear, love, hate, anger, joy? do we control our emotions, or do they control us? Do animals have emotions? How can traumatic experiences in early childhoodExpand
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