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Tricyclic Antidepressive Agents

Known as: Tricyclic Antidepressant, antidepressants tricyclics, Antidepressants, Tricyclic 
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and… 
National Institutes of Health

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2-hydroxydesipramineAmitriptylineAmoxapineClomipramine
Affective Disorders, PsychoticIn BloodTricyclic Antidepressant [EPC]Tricyclic antidepressants positive:Prid:Pt:Urine:Nom:Confirm

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Antidepressive Agents

Papers overview

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Highly Cited
2009
Highly Cited
2009
Tricyclic antidepressant agents. I. Comparison of the inhibition of the uptake of 3-H-noradrenaline and 14-C-5-hydroxytryptamine in slices and crude synaptosome preparations of the midbrain…
The simultaneous uptake of 3-H-l-noradrenaline (NA) and 14-C-5-hydroxytryptamine (5-HT) in slices from the midbrain-hypothalamus… 
Highly Cited
1988
Highly Cited
1988
Impaired cholecystokinin secretion in bulimia nervosa.
Bulimia nervosa is a prevalent disorder of unknown cause, characterized by recurrent episodes of uncontrollable eating. In the… 
Highly Cited
1982
Highly Cited
1982
Cardiovascular effects of tricyclic antidepressants in depressed patients with chronic heart disease.
Twenty-four depressed patients with heart disease were treated for four weeks in a double-blind trial of imipramine, doxepin, or… 
Review
1982
Review
1982
Clinical Pharmacokinetics of Oral Activated Charcoal in Acute Intoxications
SummaryActivated charcoal has the ability to adsorb a wide variety of substances onto its surface. This property can be applied… 
Review
1981
Review
1981
Delusional depression. A distinct clinical entity?
The prognostic importance of delusions in the depressive syndrome had been a major focus of study before somatic therapies were… 
Highly Cited
1981
Highly Cited
1981
α2-Adrenoreceptors in rat brain are decreased after long-term tricyclic antidepressant drug treatment
Highly Cited
1980
Highly Cited
1980
Repeated tricyclics induce a progressive dopamine autoreceptor subsensitivity independent of daily drug treatment
Dopamine (DA) has largely been ignored in considering possible mechanisms underlying the therapeutic effects of tricyclic anti… 
Highly Cited
1979
Highly Cited
1979
Effect of electroconvulsive shock on monoaminergic receptor binding sites in rat brain
CHRONIC administration of either tricyclic antidepressant drugs or monoamine oxidase inhibitors, which are effective in the… 
Highly Cited
1977
Highly Cited
1977
Cardiac antiarrhythmic effect of imipramine hydrochloride.
Over 20 million prescriptions are written annually for tricyclic antidepressants.1 The cardiotoxicity of overdosage is well… 
Review
1972
Review
1972
On the Slowness of Action of Tricyclic Antidepressant Drugs
It is widely believed that tricyclic antidepressants such as imipramine bring little benefit for ten days, that three or four… 
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