Skip to search formSkip to main contentSkip to account menu

tabersonine

Known as: Aspidospermidine-3-carboxylic acid, 2,3,6,7-tetradehydro-, methyl ester, (5alpha,12beta,19alpha)- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (2)

Indole AlkaloidsQuinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
Completion of the seven-step pathway from tabersonine to the anticancer drug precursor vindoline and its assembly in yeast
Significance Bioinformatics and virus-induced gene silencing (VIGS)-guided gene discovery combined with biochemical enzyme assays… 
Review
2015
Review
2015
Indole Alkaloids from Catharanthus roseus: Bioproduction and Their Effect on Human Health
Catharanthus roseus is a medicinal plant belonging to the family Apocynaceae which produces terpenoid indole alkaloids (TIAs) of… 
Highly Cited
2015
Highly Cited
2015
Tabersonine inhibits amyloid fibril formation and cytotoxicity of Aβ(1-42).
The misfolding and aggregation of amyloid beta (Aβ) peptides into amyloid fibrils are key events in the amyloid cascade… 
Highly Cited
2013
Highly Cited
2013
A Pair of Tabersonine 16-Hydroxylases Initiates the Synthesis of Vindoline in an Organ-Dependent Manner in Catharanthus roseus1[C][W]
A newly identified cytochrome P450 isoform initiates the synthesis of valuable alkaloids in leaves of Catharanthus roseus by… 
Highly Cited
2011
Highly Cited
2011
The expression of 1-deoxy-D-xylulose synthase and geraniol-10-hydroxylase or anthranilate synthase increases terpenoid indole alkaloid accumulation in Catharanthus roseus hairy roots.
Highly Cited
2005
Highly Cited
2005
Localization of tabersonine 16-hydroxylase and 16-OH tabersonine-16-O-methyltransferase to leaf epidermal cells defines them as a major site of precursor biosynthesis in the vindoline pathway in…
The Madagascar periwinkle (Catharanthus roseus) produces the well known and remarkably complex anticancer dimeric alkaloids… 
Highly Cited
2002
Highly Cited
2002
Screening of Catharanthus roseus secondary metabolites by high-performance liquid chromatography.
Highly Cited
2000
Highly Cited
2000
Determination of metabolic rate-limitations by precursor feeding in Catharanthus roseus hairy root cultures.
Highly Cited
1995
Highly Cited
1995
A Cytochrome P-450 Monooxygenase Catalyzes the First Step in the Conversion of Tabersonine to Vindoline in Catharanthus roseus
Hydroxylation at the C-16 position of the indole alkaloid tabersonine has been suggested as the first step toward vindoline… 
Highly Cited
1987
Highly Cited
1987
Subcellular Localization of Enzymes Involved in Indole Alkaloid Biosynthesis in Catharanthus roseus.
The subcellular localization of enzymes involved in indole alkaloid biosynthesis in leaves of Catharanthus roseus has been… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)