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Indole Alkaloids

Known as: Alkaloids, Indole, Indole Alkaloids [Chemical/Ingredient] 
Group of alkaloids containing a benzylpyrrole group (derived from TRYPTOPHAN)
National Institutes of Health

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antagonists & inhibitors

Papers overview

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Highly Cited
2011
Highly Cited
2011
The Transcription Factor CrWRKY1 Positively Regulates the Terpenoid Indole Alkaloid Biosynthesis in Catharanthus roseus1[W][OA]
Catharanthus roseus produces a large array of terpenoid indole alkaloids (TIAs) that are an important source of natural or… 
Review
2010
Review
2010
Marine indole alkaloids: potential new drug leads for the control of depression and anxiety.
The marine environment has been explored in the search for new bioactive compounds over the last 50 years, becoming a highly… 
Highly Cited
2006
Highly Cited
2006
Gene-to-metabolite networks for terpenoid indole alkaloid biosynthesis in Catharanthus roseus cells.
Rational engineering of complicated metabolic networks involved in the production of biologically active plant compounds has been… 
Review
2005
Review
2005
Simple indole alkaloids and those with a nonrearranged monoterpenoid unit.
This review covers the literature on simple indole alkaloids and those with a nonrearranged monoterpenoid unit from the beginning… 
Review
2004
Review
2004
The Catharanthus alkaloids: pharmacognosy and biotechnology.
The Catharanthus (or Vinca) alkaloids comprise a group of about 130 terpenoid indole alkaloids. Vinblastine is now marketed for… 
Review
2004
Review
2004
Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa.
  • H. Takayama
  • Chemical & pharmaceutical bulletin
  • 2004
  • Corpus ID: 6487933
The leaves of a tropical plant, Mitragyna speciosa KORTH (Rubiaceae), have been traditionally used as a substitute for opium… 
Review
2001
Review
2001
ALKALOID BIOSYNTHESIS IN PLANTS: Biochemistry, Cell Biology, Molecular Regulation, and Metabolic Engineering Applications.
  • P. Facchini
  • Annual review of plant physiology and plant…
  • 2001
  • Corpus ID: 24303274
Recent advances in the cell, developmental, and molecular biology of alkaloid biosynthesis have heightened our appreciation for… 
Highly Cited
2000
Highly Cited
2000
Indole alkaloid biosynthesis in Catharanthus roseus: new enzyme activities and identification of cytochrome P450 CYP72A1 as secologanin synthase.
The molecular characterization of CYP72A1 from Catharanthus roseus (Madagascar periwinkle) was described nearly a decade ago, but… 
Highly Cited
1994
Highly Cited
1994
Tremorgenic indole alkaloids potently inhibit smooth muscle high-conductance calcium-activated potassium channels.
Tremorgenic indole alkaloids produce neurological disorders (e.g., staggers syndromes) in ruminants. The mode of action of these… 
Review
1990
Review
1990
The discovery of the vinca alkaloids--chemotherapeutic agents against cancer.
  • R. Noble
  • Biochemistry and cell biology = Biochimie et…
  • 1990
  • Corpus ID: 40386740
In folklore medicine, extracts of the leaves of the subtropical plant Catharanthus roseus (L.) G. Don (sometimes known as… 
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