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- Publications
- Influence
Elicitor signal transduction leading to production of plant secondary metabolites.
- J. Zhao, L. C. Davis, R. Verpoorte
- Biology, Medicine
- Biotechnology advances
- 1 June 2005
Plant secondary metabolites are unique sources for pharmaceuticals, food additives, flavors, and other industrial materials. Accumulation of such metabolites often occurs in plants subjected to… Expand
NMR-based metabolomic analysis of plants
- H. K. Kim, Y. Choi, R. Verpoorte
- Chemistry, Medicine
- Nature Protocols
- 25 February 2010
Nuclear magnetic resonance (NMR)-based metabolomics has many applications in plant science. Metabolomics can be used in functional genomics and to differentiate plants from different origin, or after… Expand
The Catharanthus alkaloids: pharmacognosy and biotechnology.
- R. van der Heijden, D. Jacobs, Wim Snoeijer, D. Hallard, R. Verpoorte
- Biology, Medicine
- Current medicinal chemistry
- 29 February 2004
The Catharanthus (or Vinca) alkaloids comprise a group of about 130 terpenoid indole alkaloids. Vinblastine is now marketed for more than 40 years as an anticancer drug and became a true lead… Expand
Natural deep eutectic solvents as new potential media for green technology.
- Y. Dai, J. van Spronsen, G. Witkamp, R. Verpoorte, Y. Choi
- Chemistry, Medicine
- Analytica chimica acta
- 5 March 2013
Developing new green solvents is one of the key subjects in Green Chemistry. Ionic liquids (ILs) and deep eutectic solvents, thus, have been paid great attention to replace current harsh organic… Expand
Geraniol 10‐hydroxylase1, a cytochrome P450 enzyme involved in terpenoid indole alkaloid biosynthesis
- G. Collu, N. Unver, A. Peltenburg-Looman, R. van der Heijden, R. Verpoorte, J. Memelink
- Biology, Medicine
- FEBS letters
- 16 November 2001
Geraniol 10‐hydroxylase (G10H) is a cytochrome P450 monooxygenase involved in the biosynthesis of iridoid monoterpenoids and several classes of monoterpenoid alkaloids found in a diverse range of… Expand
NMR-based plant metabolomics: where do we stand, where do we go?
- H. K. Kim, Y. Choi, R. Verpoorte
- Biology, Medicine
- Trends in biotechnology
- 1 June 2011
NMR-based metabolomics is an important tool for studying biological systems and has been applied in various organisms, including animals, plants and microbes. NMR is able to provide a 'holistic view'… Expand
The seco-iridoid pathway from Catharanthus roseus
- Karel Miettinen, Lemeng Dong, +14 authors D. Werck-Reichhart
- Biology, Medicine
- Nature communications
- 7 April 2014
The (seco)iridoids and their derivatives, the monoterpenoid indole alkaloids (MIAs), form two large families of plant-derived bioactive compounds with a wide spectrum of high-value pharmacological… Expand
Natural deep eutectic solvents as a new extraction media for phenolic metabolites in Carthamus tinctorius L.
- Y. Dai, G. Witkamp, R. Verpoorte, Y. Choi
- Chemistry, Medicine
- Analytical chemistry
- 11 June 2013
Developing green solvents with low toxicity and cost is an important issue for the biochemical industry. Synthetic ionic liquids and deep eutectic solvents have received considerable attention due to… Expand
Cultivation of medicinal and aromatic plants for specialty industrial materials
- Andrea Lubbe, Andrea Lubbe, R. Verpoorte
- Business
- 1 July 2011
Specialty materials such as essential oils, pharmaceuticals, colorants, dyes, cosmetics and biocides are obtained from plants. Many species of medicinal and aromatic plants (MAPs) are cultivated for… Expand
Coordinated regulation of two indole alkaloid biosynthetic genes from Catharanthus roseus by auxin and elicitors
- G. Pasquali, O. Goddijn, +4 authors J. Memelink
- Biology, Medicine
- Plant Molecular Biology
- 1 April 1992
Catharanthus roseus (periwinkle) produces a wide range of terpenoid indole alkaloids, including several pharmaceutically important compounds, from the intermediate strictosidine. The complete mRNA… Expand