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Extraction and characterisation of pepsin-solubilised collagens from the skin of bigeye snapper (Priacanthus tayenus and Priacanthus macracanthus).
TLDR
Tongol tuna pepin could be used as a replacement for mammalian pepsin in PSC extraction, and a slight difference in P SC properties was found.
Activity of andrographolide against chikungunya virus infection
TLDR
Andrographolide showed good inhibition of CHIKV infection and reduced virus production by approximately 3log10 with a 50% effective concentration (EC50) of 77 μM without cytotoxicity, showing the potential to be developed further as an anti-CHIKV therapeutic agent.
Proteomic Analysis of Chikungunya Virus Infected Microgial Cells
TLDR
Analysis of the protein profile in response to infection did not support a global inhibition of either normal or IRES-mediated translation, but was consistent with the targeting of specific cellular pathways including those regulating innate antiviral mechanisms.
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