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sparfosic acid

Known as: N-(phosphonoacetyl)-L-aspartic acid, PALA, n-phosphonacetyl-l-aspartic acid 
A stable transition state analogue for an aspartate transcarbamylase-catalyzed reaction with antineoplastic activity. Sparfosic acid is a stable… 
National Institutes of Health

Papers overview

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Highly Cited
1996
Highly Cited
1996
Because the N‐ and C‐terminal amino acids of the catalytic (c) polypeptide chains of Escherichia coli aspartate transcarbamoylase… 
1995
1995
The regulation of aspartate transcarbamylase (ATCase) involves various conformational changes, including a large quaternary… 
1995
1995
The rat cell line REF52 is not permissive for gene amplification. Simian virus 40 tumor (T) antigen converts these cells to a… 
1983
1983
Eleven independent lines of Syrian hamster cells were selected by using very low levels of N-(phosphonacetyl)-L-aspartate (PALA… 
1979
1979
Several biochemical parameters were examined relative to the sensitivity or resistance of representative rodent tumors to N… 
1973
1973
Abstract Spectrophotometric titration studies at pH 8.0 have revealed that pyridoxal 5'-phosphate binds as a Schiff base to the…