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Aspartic Acid

Known as: acid aspartic, D, (S)-2-aminobutanedioic acid 
A non-essential amino acid in humans, Aspartic Acid has an overall negative charge and plays an important role in the synthesis of other amino acids… 
National Institutes of Health

Related topics

Related topics

49 relations

Narrower (30)

3-methylaspartic acidAKF 94Ammonium AspartateIEM1944

Broader (3)

ASPA geneAmino AcidsNeurotransmitters
Ethanol 0.62 ML/ML Topical GelIn BloodNutritional and Metabolic DiseasesPERIKABIVEN INJ

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1999
Review
1999
Memantine is a clinically well tolerated N-methyl-d-aspartate (NMDA) receptor antagonist—a review of preclinical data
Highly Cited
1995
Highly Cited
1995
D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release.
Using an antibody highly specific for D-serine conjugated to glutaraldehyde, we have localized endogenous D-serine in rat brain… 
Highly Cited
1995
Highly Cited
1995
Regulation of adult neurogenesis by excitatory input and NMDA receptor activation in the dentate gyrus
The effects of afferent input and N-methyl-D-aspartate (NMDA) receptor activation on neurogenesis were examined in an intact… 
Highly Cited
1993
Highly Cited
1993
Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.
Highly Cited
1993
Highly Cited
1993
Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.
High levels of extracellular K+ ensure proper development and prolong survival of cerebellar granule neurons in culture. We find… 
Highly Cited
1987
Highly Cited
1987
Micromolar concentrations of Zn2+ antagonize NMDA and GABA responses of hippocampal neurons
NMDA (N-methyl-D-aspartate) receptors serve as modulators of synaptic transmission in the mammalian central nervous system (CNS… 
Highly Cited
1987
Highly Cited
1987
The role of depolarization in the survival and differentiation of cerebellar granule cells in culture
Cultures greatly enriched in granule cells from early postnatal cerebellum (P8) were grown in a medium containing fetal calf… 
Highly Cited
1985
Highly Cited
1985
Amino-acid sequence of a Ca2+ + Mg2+ -dependent ATPase from rabbit muscle sarcoplasmic reticulum, deduced from its complementary DNA sequence
We have cloned and sequenced complementary DNA encoding a Ca2+-ATPase of rabbit muscle sarcoplasmic reticulum. We propose a model… 
Review
1984
Review
1984
Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors
Highly Cited
1962
Highly Cited
1962
The enzymology of control by feedback inhibition.
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