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The crystal structure of the asymmetric GroEL–GroES–(ADP)7 chaperonin complex
- Zhaohui Xu, A. Horwich, P. Sigler
- BiologyNature
- 21 August 1997
TLDR
Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA
- B. Luisi, W. Xu, Z. Otwinowski, L. Freedman, K. Yamamoto, P. Sigler
- Chemistry, BiologyNature
- 21 October 2003
Two crystal structures of the glucocorticoid receptor DNA-binding domain complexed with DNA are reported. The domain has a globular fold which contains two Zn-nucleated substructures of distinct…
The Structure of ClpB A Molecular Chaperone that Rescues Proteins from an Aggregated State
- Sukyeong Lee, M. Sowa, F. Tsai
- ChemistryCell
- 1 October 2003
The 2.0 Å crystal structure of a heterotrimeric G protein
- D. Lambright, J. Sondek, A. Bohm, N. Skiba, H. Hamm, P. Sigler
- Biology, ChemistryNature
- 25 January 1996
The structure of a heterotrimeric G protein reveals the mechanism of the nucleotide-dependent engagement of the α and βγ subunits that regulates their interaction with receptor and effector…
Crystal structure of a yeast TBP/TATA-box complex
- Youngchang Kim, J. Geiger, S. Hahn, P. Sigler
- EngineeringNature
- 7 October 1993
The 2.5 Å crystal structure of a TATA-box complex with yeast TBP shows that the eight base pairs of the TATA box bind to the concave surface of TBP by bending towards the major groove with…
The crystal structure of the bacterial chaperonln GroEL at 2.8 Å
- K. Braig, Z. Otwinowski, P. Sigler
- GeologyNature
- 13 October 1994
The crystal structure of Escherichia coli GroEL shows a porous cylinder of 14 subunits made of two nearly 7-fold rotationally symmetrical rings stacked back-to-back with dyad symmetry. The subunits…
Specific and high-affinity binding of inositol phosphates to an isolated pleckstrin homology domain.
- M. Lemmon, K. Ferguson, R. O'brien, P. Sigler, J. Schlessinger
- Biology, ChemistryProceedings of the National Academy of Sciences…
- 7 November 1995
TLDR
Structural determinants of nuclear receptor assembly on DNA direct repeats
- F. Rastinejad, T. Perlmann, R. Evans, P. Sigler
- Biology, ChemistryNature
- 18 May 1995
TLDR
THE CRYSTAL STRUCTURE OF THE BACTERIAL CHAPERONIN GROEL AT 2.8 ANGSTROMS
- K. Braig, Z. Otwinowski, P. Sigler
- Chemistry
- 15 October 1995
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