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- Publications
- Influence
Intraneuronal Abeta42 accumulation in human brain.
Alzheimer's disease (AD) is characterized by the deposition of senile plaques (SPs) and neurofibrillary tangles (NFTs) in vulnerable brain regions. SPs are composed of aggregated beta-amyloid (Abeta)… Expand
The disintegrins ADAM10 and TACE contribute to the constitutive and phorbol ester-regulated normal cleavage of the cellular prion protein.
- B. Vincent, E. Paitel, +6 authors F. Checler
- Biology, Medicine
- The Journal of biological chemistry
- 12 October 2001
We showed previously that PrPc undergoes constitutive and phorbol ester-regulated cleavage inside the 106-126 toxic domain of the protein, leading to the production of a fragment referred to as N1.… Expand
Presenilin-Dependent Transcriptional Control of the Aβ-Degrading Enzyme Neprilysin by Intracellular Domains of βAPP and APLP
- R. Pardossi-Piquard, A. Petit, +9 authors F. Checler
- Biology
- Neuron
- 19 May 2005
Amyloid beta-peptide (Abeta), which plays a central role in Alzheimer's disease, is generated by presenilin-dependent gamma-secretase cleavage of beta-amyloid precursor protein (betaAPP). We report… Expand
Presenilin-dependent transcriptional control of the Abeta-degrading enzyme neprilysin by intracellular domains of betaAPP and APLP.
- R. Pardossi-Piquard, A. Petit, +9 authors F. Checler
- Medicine
- Neuron
- 2005
Amyloid beta-peptide (Abeta), which plays a central role in Alzheimer's disease, is generated by presenilin-dependent gamma-secretase cleavage of beta-amyloid precursor protein (betaAPP). We report… Expand
Étude du benthos d'eau douce dans le haut estuaire du Saint-Laurent (Québec)
- B. Vincent
- Biology
- 1 November 1979
Nous avons etudie le benthos recolte dans 37 stations du Saint-Laurent qui sont echelonnees sur une distance de 230 km, entre le lac Saint-Pierre et l'ile aux Oies. L'examen de la repartition des… Expand
Estrogen reduces neuronal generation of Alzheimer β-amyloid peptides
Alzheimer's disease (AD) is characterized by the accumulation of cerebral plaques composed of 40- and 42-amino acid β-amyloid (Aβ) peptides, and autosomal dominant forms of AD appear to cause disease… Expand
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides.
Alzheimer's disease (AD) is characterized by the accumulation of cerebral plaques composed of 40- and 42-amino acid beta-amyloid (Abeta) peptides, and autosomal dominant forms of AD appear to cause… Expand
Assessing Species Distribution Using Google Street View: A Pilot Study with the Pine Processionary Moth
- J. Rousselet, C. Imbert, +8 authors J. Rossi
- Computer Science, Medicine
- PloS one
- 9 October 2013
TLDR
Fecundity and larval development of Monochamus galloprovincialis (Coleoptera Cerambycidae) in experimental breeding
- Fotini A. Koutroumpa, B. Vincent, G. Roux-Morabito, Carine Martin, F. Lieutier
- Biology
- Annals of Forest Science
- 1 October 2008
Abstract•The study aimed at clarifying basic life traits (fecundity, mortality and development) of Monochamus galloprovincialis, the vector of Bursaphelenchus xylophilus, the causative agent of the… Expand
Presenilin-Dependent γ-Secretase-Mediated Control of p53-Associated Cell Death in Alzheimer's Disease
- C. Alvès da Costa, C. Sunyach, +7 authors F. Checler
- Biology
- The Journal of Neuroscience
- 7 June 2006
Presenilins (PSs) are part of the γ-secretase complex that produces the amyloid β-peptide (Aβ) from its precursor [β-amyloid precursor protein (βAPP)]. Mutations in PS that cause familial Alzheimer's… Expand