serine, D-

Known as: D-serine 
A non-essential amino acid and dextro isomer of serine with antipsychotic activity. D-serine is a selective full agonist at the glycine site of N… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1951-2018
05010019512017

Papers overview

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Highly Cited
2010
Highly Cited
2010
Long-term potentiation (LTP) of synaptic transmission provides an experimental model for studying mechanisms of memory. The… (More)
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Highly Cited
2006
Highly Cited
2006
The NMDA receptor is a key player in excitatory transmission and synaptic plasticity in the central nervous system. Its… (More)
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Highly Cited
2005
Highly Cited
2005
The gliotransmitter D-serine is released upon (S)-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate and… (More)
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Highly Cited
2005
Highly Cited
2005
Several lines of evidence suggest that D-serine, an endogenous agonist of the glycine site on the NMDA receptors, might play a… (More)
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Highly Cited
2003
Highly Cited
2003
Repetitive correlated activation of pre- and postsynaptic neurons induced long-term potentiation (LTP) of synaptic transmission… (More)
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Highly Cited
2000
Highly Cited
2000
Functional activity of N-methyl-D-aspartate (NMDA) receptors requires both glutamate binding and the binding of an endogenous… (More)
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Highly Cited
1999
Highly Cited
1999
Although D amino acids are prominent in bacteria, they generally are thought not to occur in mammals. Recently, high levels of D… (More)
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Highly Cited
1999
Highly Cited
1999
High levels of D-serine occur in mammalian brain, where it appears to be an endogenous ligand of the glycine site of N-methyl-D… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Hypofunction of N-methyl-D-aspartate (NMDA) subtype glutamate receptor has been implicated in the pathophysiology of… (More)
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Highly Cited
1995
Highly Cited
1995
Using an antibody highly specific for D-serine conjugated to glutaraldehyde, we have localized endogenous D-serine in rat brain… (More)
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