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saruplase

Known as: prourokinase (enzyme-activating), recombinant unglycosylated single-chain urokinase-type plasminogen activator, pro-urokinase 
National Institutes of Health

Related topics

Related topics

4 relations

Narrower (1)

A-74187

Broader (3)

Fibrinolytic AgentsRecombinant ProteinsUrokinase

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Safety and efficacy of prourokinase injection in patients with ST-elevation myocardial infarction: phase IV clinical trials of the prourokinase phase study
AbstractTo evaluate the safety and efficacy in terms of infarct-related artery (IRA) patency of prourokinase (proUK) injection… 
Highly Cited
2008
Highly Cited
2008
Heterologous Expression And Genetic Engineering of the Phenalinolactone Biosynthetic Gene Cluster by Using Red/ET Recombineering
The heterologous expression of natural product biosynthetic pathways is of increasing interest in biotechnology and drug… 
2006
2006
Evaluation of the Antibacterial Spectrum of Drosocin Analogues
Drosocin is a 19‐mer, cationic antimicrobial peptide from Drosophila melanogaster. The aim of the study was to examine the… 
2006
2006
Thrombolysis vs. bleeding from hemostatic sites by a prourokinase mutant compared with tissue plasminogen activator
Summary.  Background: A single site mutant (M5) of prourokinase (proUK) was developed to make proUK less vulnerable to… 
Highly Cited
2004
Highly Cited
2004
Cytoprotection by Achyrocline satureioides (Lam) D.C. and some of its main flavonoids against oxidative stress.
2004
2004
Effect of transfection and passage number of ear fibroblasts on in vitro development of bovine transgenic nuclear transfer embryos.
The objective of this study was to determine if the transfection of human prourokinase (ProU) gene and passage number of… 
2002
2002
Glycosylation affects the rate of traffic of the Shaker potassium channel through the secretory pathway.
We have examined the effect of glycosylation on the traffic of the voltage-gated Shaker potassium channel through the secretory… 
Highly Cited
2000
Highly Cited
2000
Self-assembly of recombinant prion protein of 106 residues.
The central event in the pathogenesis of prion diseases is a profound conformational change of the prion protein (PrP) from an… 
Highly Cited
1997
Highly Cited
1997
Synergistic roles of HslVU and other ATP-dependent proteases in controlling in vivo turnover of sigma32 and abnormal proteins in Escherichia coli
Production of abnormal proteins during steady-state growth induces the heat shock response by stabilizing normally unstable… 
1994
1994
New recombinant glycosylated prourokinase for treatment of patients with acute myocardial infarction. Prourokinase Study Group.
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