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Fibrinolytic Agents

Known as: thrombolytic drug, [BL115] THROMBOLYTICS, Thrombolytic Drugs 
Any agent capable of dissolving an existing blood clot in order to reperfuse the blocked blood vessel.
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
2008;133;113-122 Chest Holger J. Schünemann, Deborah Cook and Gordon Guyatt Guidelines (8th Edition) Physicians Evidence-Based… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Whether intravenous tissue plasminogen activator (alteplase) is effective beyond 3 h after onset of acute ischaemic… Expand
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Highly Cited
2005
Highly Cited
2005
BACKGROUND A substantial proportion of patients receiving fibrinolytic therapy for myocardial infarction with ST-segment… Expand
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Highly Cited
2004
Highly Cited
2004
This article concerning the pharmacokinetics and pharmacodynamics of vitamin K antagonists (VKAs) is part of the Seventh American… Expand
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Highly Cited
1999
Highly Cited
1999
BACKGROUND AND PURPOSE The Barthel Index (BI) and the Modified Rankin Scale (MRS) are commonly used scales that measure… Expand
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Highly Cited
1998
Highly Cited
1998
Summary Background Thrombolysis for acute ischaemic stroke has been investigated in several clinical trials, with variable… Expand
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Highly Cited
1996
Highly Cited
1996
BACKGROUND Although the Thrombolysis in Myocardial Infarction (TIMI) flow grade is valuable and widely used qualitative measure… Expand
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Highly Cited
1993
Highly Cited
1993
Survival after acute myocardial infarction has been enhanced by treatment with thrombolytic agents, aspirin, and beta… Expand
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Highly Cited
1992
Highly Cited
1992
BACKGROUND The large volume of published randomized, controlled trials has led to a need for meta-analyses to track therapeutic… Expand
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Highly Cited
1987
Highly Cited
1987
Intravenous administration of 80 mg of recombinant tissue plasminogen activator (rt-PA, 40, 20, and 20 mg in successive hours… Expand
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