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Fibrinolytic Agents

Known as: thrombolytic drug, [BL115] THROMBOLYTICS, Thrombolytic Drugs 
Any agent capable of dissolving an existing blood clot in order to reperfuse the blocked blood vessel.
National Institutes of Health

Related topics

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Narrower (41)

9-O-methanoprostaglandin IAncrodAnistreplaseAspirin
Antithrombotic AgentsFibrinolysisIn BloodProtein C

Papers overview

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Highly Cited
2000
Highly Cited
2000
Combined thrombolytic and anticoagulant therapy for venous thrombosis in children.
Highly Cited
1993
Highly Cited
1993
Body Surface Potential Mapping of ST Segment Changes in Acute Myocardial Infarction Implications for ECG Enrollment Criteria for Thrombolytic Therapy
BackgroundSeveral large, randomized clinical trials have shown that early thrombolytic therapy substantially reduces early… 
Highly Cited
1990
Highly Cited
1990
Fate of patients with acute myocardial infarction with patency of the infarct-related vessel achieved with successful thrombolysis versus rescue angioplasty.
Highly Cited
1990
Highly Cited
1990
Reinfarction after thrombolytic therapy for acute myocardial infarction followed by conservative management: incidence and effect of smoking.
Highly Cited
1989
Highly Cited
1989
Monitoring of fibrin generation during thrombolytic therapy of acute myocardial infarction with recombinant tissue-type plasminogen activator.
Fibrinopeptide A (FPA) is a very sensitive marker of fibrin generation in vivo. Because an imbalance between thrombogenic and… 
Highly Cited
1988
Highly Cited
1988
Electrocardiographic prediction of coronary artery patency after thrombolytic treatment in acute myocardial infarction: use of the ST segment as a non-invasive marker.
The predictive value of the measurement of changes in ST segment elevation was assessed as a non-invasive marker of coronary… 
Highly Cited
1988
Highly Cited
1988
Pharmacokinetics and thrombolytic properties of deletion mutants of human tissue-type plasminogen activator in rabbits.
The following mutants of human tissue-type plasminogen activator (t-PA) were constructed by deletion mutagenesis of t-PA cDNA… 
Highly Cited
1988
Highly Cited
1988
Effects of thrombolytic therapy in unstable angina: clinical and angiographic results.
Highly Cited
1982
Highly Cited
1982
Thrombolysis with human extrinsic (tissue-type) plasminogen activator in dogs with femoral vein thrombosis.
Extrinsic (tissue-type) plasminogen activator (plasminogen activator) was isolated either as a single-chain or as a two-chain… 
Highly Cited
1975
Highly Cited
1975
Prostaglandin d2 as a potential antithrombotic agent.
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