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Protein C
Known as:
Protein C (Homo sapiens)
, Protein C [Chemical/Ingredient]
A vitamin-K dependent zymogen present in the blood, which, upon activation by thrombin and thrombomodulin exerts anticoagulant properties by…
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National Institutes of Health
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Related topics
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33 relations
Activated protein C resistance:Imp:Pt:PPP:Nom
Activated protein C resistance:PrThr:Pt:PPP:Ord:Coag
Activated protein C resistance:TRto:Pt:PPP:Qn:Coag
Fibrinolytic Agents
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Broader (6)
Anticoagulants
Blood Proteins
Enzyme Inhibitors
Enzyme Precursors
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Narrower (6)
Ceprotin
Kcentra
drotrecogin alfa
protein C Yonago
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Exploring the role of the phospholipid ligand in endothelial protein C receptor: A molecular dynamics study
F. Chiappori
,
I. Merelli
,
L. Milanesi
,
E. Rovida
Proteins: Structure, Function, and Bioinformatics
2010
Corpus ID: 36809679
Endothelial protein C receptor (EPCR) is a CD1‐like transmembrane glycoprotein with important regulatory roles in protein C (PC…
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2005
2005
The Affinity of Protein C for the Thrombin·Thrombomodulin Complex Is Determined in a Primary Way by Active Site-dependent Interactions*
Genmin Lu
,
S. Chhum
,
S. Krishnaswamy
Journal of Biological Chemistry
2005
Corpus ID: 9002907
The interaction of thrombin (IIa) with thrombomodulin (TM) is essential for the efficient activation of protein C (PC…
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Review
2002
Review
2002
Inherited Abnormalities in the protein C Activation Pathway
F. España
,
P. Medina
,
S. Navarro
,
A. Estellés
,
J. Aznar
Pathophysiology of Haemostasis and Thrombosis
2002
Corpus ID: 5495799
The protein C (PC) anticoagulant pathway plays a crucial role in the regulation of fibrin formation via proteolytic degradation…
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1999
1999
Brain-specific protein C activation during carotid artery occlusion in humans.
R. Macko
,
L. Killewich
,
José A. Fernández
,
D. K. Cox
,
A. Gruber
,
J. Griffin
Stroke
1999
Corpus ID: 2204838
BACKGROUND AND PURPOSE Activation of plasma protein C (PC) zymogen by thrombin-thrombomodulin at the endothelial surface is an…
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1997
1997
Highly conserved residue arginine-15 is required for the Ca2+-dependent properties of the gamma-carboxyglutamic acid domain of human anticoagulation protein C and activated protein C.
A. Thariath
,
F. Castellino
Biochemical Journal
1997
Corpus ID: 21366374
The function of the rigidly conserved amino acid residue R15 in the Ca2+/phospholipid-dependent properties of the gamma…
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1994
1994
High Affinity Binding Sites for Activated Protein C and Protein C on Cultured Human Umbilical Vein Endothelial Cells
Neelesh Bangalore
,
W. Drohan
,
C. Orthner
Thrombosis and Haemostasis
1994
Corpus ID: 34395062
Summary Activated protein C (APC) is an antithrombotic serine proteinase having anticoagulant, profibrinolytic and anti…
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1992
1992
Isolation and characterization of a mouse protein C cDNA.
Norihiro Tada
,
Masahiro Sato
,
Atsushi Tsujimura
,
Reiko Iwase
,
Tamotsu Hashimoto-Gotoh
Journal of Biochemistry (Tokyo)
1992
Corpus ID: 26036977
Protein C (PC) is a vitamin K-dependent serine protease, a deficiency of which results in thrombus. There is no spontaneously…
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1989
1989
Molecular Forms of Human Protein C: Comparison and Distribution in Human Adult Plasma
Brian S. Greffe
,
M. Manco‐Johnson
,
R. Marlar
Thrombosis and Haemostasis
1989
Corpus ID: 24982171
Summary Protein C (PC) is a vitamin K-dependent protein which functions as both an anticoagulant and profibrinolytic. It is…
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1986
1986
Decrease and rapid recovery of protein C after plasma exchange
P. Mannucci
,
A. D’Angelo
,
+6 authors
P. Walsh
Transfusion
1986
Corpus ID: 25845360
The anticoagulant protein, protein C (PC), was measured after 40 plasma exchanges (PEs) in 26 patients treated for a variety of…
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1986
1986
Plasma levels of protein C and vitamin K-dependent coagulation factors in patients on long-term oral anticoagulant therapy.
H. Takahashi
,
M. Hanano
,
+7 authors
A. Shibata
Tohoku journal of experimental medicine
1986
Corpus ID: 11282889
Plasma levels of protein C (PC) and vitamin K-dependent coagulation factors (factors II, VII, IX and X) were measured in 100…
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