Enzyme Precursors

Known as: Enzyme Precursors [Chemical/Ingredient], proenzyme, Proenzymes 
Physiologically inactive substances that can be converted to active enzymes.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1945-2018
010020019452017

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
nature medicine advance online publication Despite the absence of any overt infection or definitive evidence of autoantigen… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Apoptosis is orchestrated by the concerted action of caspases, activated in a minimal two-step proteolytic cascade. Existing data… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Survivin is a member of the inhibitor of apoptosis protein (IAP) family. We investigated the antiapoptotic mechanism of Survivin… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Two reports from China have suggested that arsenic trioxide can induce complete remissions in patients with acute… (More)
Is this relevant?
Highly Cited
1997
Highly Cited
1997
There is compelling evidence that members of the caspase (interleukin-1beta converting enzyme/CED-3) family of cysteine proteases… (More)
Is this relevant?
Highly Cited
1996
Highly Cited
1996
It is now clear that members of the ICE/CED-3 protease Philadelphia, Pennsylvania 19107–5541 family play key biological roles in… (More)
  • figure 1
Is this relevant?
Highly Cited
1995
Highly Cited
1995
The protease responsible for the cleavage of poly(ADP-ribose) polymerase and necessary for apoptosis has been purified and… (More)
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Although the mechanism of mammalian apoptosis has not been elucidated, a protease of the CED-3/ICE family is anticipated to be a… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1995
Highly Cited
1995
Matrix metalloproteases are secreted by mammalian cells as zymogens and, upon activation, initiate tissue remodeling by… (More)
Is this relevant?
Highly Cited
1991
Highly Cited
1991
We isolated a cDNA encoding a functional human thrombin receptor by direct expression cloning in Xenopus oocytes. mRNA encoding… (More)
Is this relevant?