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Enzyme Precursors

Known as: Enzyme Precursors [Chemical/Ingredient], proenzyme, Proenzymes 
Physiologically inactive substances that can be converted to active enzymes.
National Institutes of Health

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ChymotrypsinogenEapB protein, Cryphonectria parasiticaHis-S-SStp protein, Pisum sativumHppA protein, Helicobacter pylori
EnzymesIn BloodProcess of secretionProtein Precursors

Papers overview

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Highly Cited
2001
Highly Cited
2001
Sequential-replenishment mechanism of exocytosis in pancreatic acini
Here we report exocytosis of zymogen granules, as examined by multiphoton excitation imaging in intact pancreatic acini… 
Highly Cited
1997
Highly Cited
1997
Ancient origin of the complement lectin pathway revealed by molecular cloning of mannan binding protein-associated serine protease from a urochordate, the Japanese ascidian, Halocynthia roretzi.
Recent identification of a C3-like gene in sea urchins revealed the presence of a complement system in invertebrates. To… 
Highly Cited
1996
Highly Cited
1996
Molecular Ordering of Apoptotic Mammalian CED-3/ICE-like Proteases*
Apoptosis is executed by cysteine proteases belonging to the CED-3/ICE family, which, unlike other mammalian cysteine proteases… 
Highly Cited
1992
Highly Cited
1992
Domain structure of human 72-kDa gelatinase/type IV collagenase. Characterization of proteolytic activity and identification of the tissue inhibitor of metalloproteinase-2 (TIMP-2) binding regions.
Highly Cited
1989
Highly Cited
1989
Characterization of gelatinase from pig polymorphonuclear leucocytes. A metalloproteinase resembling tumour type IV collagenase.
The metalloproteinase 'gelatinase' stored in the granules of pig polymorphonuclear leucocytes has been purified in the latent… 
Highly Cited
1975
Highly Cited
1975
Collagenase production by human skin fibroblasts.
Highly Cited
1974
Highly Cited
1974
Increased protease levels in transformed cells: a casein overlay assay for the detection of plasminogen activator production.
Highly Cited
1970
Highly Cited
1970
Studies on phospholipase A and its zymogen from porcine pancreas. 3. Action of the enzyme on short-chain lecithins.
Highly Cited
1963
Highly Cited
1963
SYNTHESIS AND MIGRATION OF PROTEINS IN THE CELLS OF THE EXOCRINE PANCREAS AS REVEALED BY SPECIFIC ACTIVITY DETERMINATION FROM RADIOAUTOGRAPHS
Radioautographs of pancreatic acinar cells were prepared in rats and mice sacrificed at various times after injection of leucine… 
Highly Cited
1954
Highly Cited
1954
Membrane structures of cytoplasm and mitochondria in exocrine cells of mouse pancreas as revealed by high resolution electron microscopy.
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