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Rivaroxaban versus warfarin in nonvalvular atrial fibrillation.
In patients with atrial fibrillation, rivaroxaban was noninferior to warfarin for the prevention of stroke or systemic embolism and there was no significant between-group difference in the risk of major bleeding, although intracranial and fatal bleeding occurred less frequently in the rivroxaban group. Expand
A brief self-administered questionnaire to determine functional capacity (the Duke Activity Status Index).
The Duke Activity Status Index is a valid measure of functional capacity that can be obtained by self-administered questionnaire and correlated well with peak oxygen uptake. Expand
Evaluating the yield of medical tests.
The treadmill exercise test is shown to provide surprisingly little prognostic information beyond that obtained from basic clinical measurements. Expand
Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes.
When added to statin therapy, ezetimibe resulted in incremental lowering of LDL cholesterol levels and improved cardiovascular outcomes, and lowering LDL cholesterol to levels below previous targets provided additional benefit. Expand
Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both.
Valsartan is as effective as captopril in patients who are at high risk for cardiovascular events after myocardial infarction and the combination of the two on mortality in this population of patients. Expand
Relation between renal dysfunction and cardiovascular outcomes after myocardial infarction.
Even mild renal disease, as assessed by the estimated GFR, should be considered a major risk factor for cardiovascular complications after a myocardial infarction. Expand
ACC/AHA 2002 guideline update for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction--summary article: a report of the American College of
The present guidelines supersede the 1994 guidelines and summarize both the evidence and expert opinion and provide final recommendations for both patient evaluation and therapy. Expand
ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task
Angina/Non-ST-Elevation Myocardial Infarction : ACC/AHA 2007 Guidelines for the Management of Patients With Unstable ISSN: 1524-4539 Copyright © 2007 American Heart Association. All rights reserved.Expand
ACC/AHA guidelines for the management of patients with acute myocardial infarction. A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines
The American College of Cardiology and the American Heart Association request that the following format be used when citing this document: Ryan TJ, Antman EM, Brooks NH, Califf RM, Hillis LD,Expand