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Anistreplase

Known as: t-plasminogen activator, tPA, t- PA 
An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an… 
National Institutes of Health

Related topics

Related topics

28 relations

Narrower (3)

BRL-26921EminaseIminase
Brain NeoplasmsCerebral InfarctionCerebrovascular TraumaCongenital arteriovenous malformation

Broader (1)

Fibrinolytic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
1997
Review
1997
TIMI grade 3 flow and reocclusion after intravenous thrombolytic therapy: a pooled analysis.
Review
1996
Review
1996
Liver rupture after cardiopulmonary resuscitation in a patient receiving thrombolytic therapy.
1995
1995
Flow cytometry reveals activated GP IIb-IIIa complexes on platelets from patients undergoing thrombolytic therapy after acute myocardial infarction.
We report the detection of activated GP IIb-IIIa complexes on platelets of patients undergoing thrombolytic therapy after acute… 
1995
1995
The European Myocardial Infarction Project: an assessment of pre-hospital thrombolysis.
1995
1995
Human Anti-Streptokinase Antibodies Induce Platelet Aggregation in an Fc Receptor (CD32) Dependent Manner
Summary Exposure to streptokinase (SK) elicits anti-SK antibodies (Abs), which inhibit fibrinolysis and induce platelet… 
1990
1990
Reduction in hospital time to thrombolytic therapy by audit of policy guidelines.
Despite the importance of early thrombolysis in the treatment of acute myocardial infarction, unacceptable delays in drug… 
1988
1988
Effect of reperfusion on electrocardiographic and enzymatic infarct size: results of a randomized multicenter study of intravenous anisoylated plasminogen streptokinase activator complex (APSAC…
Highly Cited
1987
Highly Cited
1987
Anisoylated plasminogen streptokinase activator complex in acute myocardial infarction: a placebo-controlled arteriographic coronary recanalization study.
Highly Cited
1986
Highly Cited
1986
Clinical effects and kinetic properties of intravenous APSAC--anisoylated plasminogen-streptokinase activator complex (BRL 26921) in acute myocardial infarction.
Highly Cited
1986
Highly Cited
1986
Coronary thrombolysis during acute myocardial infarction by intravenous BRL 26921, a new anisoylated plasminogen-streptokinase activator complex.
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