Anistreplase

Known as: t-plasminogen activator, tPA, t- PA 
An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an… (More)

Topic mentions per year

Topic mentions per year

1985-2017
0204019852017

Papers overview

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1997
1997
This randomized, double-blind trial in 311 patients with acute myocardial infarction has shown that very early therapy with… (More)
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1995
1995
We report the detection of activated GP IIb-IIIa complexes on platelets of patients undergoing thrombolytic therapy after acute… (More)
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1994
1994
OBJECTIVES Our aim was to determine the time saved by administration of thrombolytic therapy at home rather than in the hospital… (More)
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1994
1994
OBJECTIVES The aim of our study was to determine a superior thrombolytic regimen from three: anistreplase (APSAC), front-loaded… (More)
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1994
1994
BACKGROUND Thrombolytic agents used clinically rely on the activation of plasminogen to plasmin. Plasmin possesses multiple… (More)
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Highly Cited
1992
Highly Cited
1992
  • BMJ
  • 1992
OBJECTIVE To assess the feasibility, safety, and efficacy of domiciliary thrombolysis by general practitioners. DESIGN… (More)
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1992
1992
Thrombolysis with recombinant tissue-type plasminogen activator (rt-PA) and anisoylated plasminogen streptokinase activator… (More)
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1990
1990
128 patients with acute myocardial infarction of duration 6 h or less were randomised in double-blind fashion to receive 30 U… (More)
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1989
1989
Thrombolytic treatment efficacy is greater when the delay between onset of pain and treatment is short. To give treatment before… (More)
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1988
1988
A multicenter randomized trial of anisoylated plasminogen streptokinase activator complex (APSAC) versus heparin in patients with… (More)
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