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Anistreplase

Known as: t-plasminogen activator, tPA, t- PA 
An acylated inactive complex of streptokinase and human lysine-plasminogen. After injection, the acyl group is slowly hydrolyzed, producing an… 
National Institutes of Health

Related topics

Related topics

28 relations

Narrower (3)

BRL-26921EminaseIminase
Brain NeoplasmsCerebral InfarctionCerebrovascular TraumaCongenital arteriovenous malformation

Broader (1)

Fibrinolytic Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1998
1998
Multivariate associates of QT dispersion in patients with acute myocardial infarction: primacy of patency status of the infarct-related artery. TEAM-3 Investigators. Third trial of Thrombolysis with…
Review
1995
Review
1995
Fibrinolytic Agents: Mechanisms of Activity and Pharmacology
Fibrinolytic (thrombolytic) agents activate the fibrinolytic system by conversion of the inactive proenzyme, plasminogen into the… 
Highly Cited
1994
Highly Cited
1994
History of drugs for thrombotic disease. Discovery, development, and directions for the future.
The history of the antithrombotic agents--aspirin, heparin, warfarin, and the thrombolytics--is a rich and lively odyssey of… 
Highly Cited
1992
Highly Cited
1992
Thrombolysis in Patients With Unstable Angina Improves the Angiographic but Not the Clinical Outcome: Results of UNASEM, A Multicenter, Randomized, Placebo‐Controlled, Clinical Trial With…
BackgroundThe value of thrombolytic therapy in unstable angina is unclear. Methods and ResultsTo study this problem, 159 patients… 
Review
1992
Review
1992
Clinical risks of thrombolytic therapy.
Highly Cited
1992
Highly Cited
1992
Feasibility, safety, and efficacy of domiciliary thrombolysis by general practitioners: Grampian region early anistreplase trial. GREAT Group.
OBJECTIVE--To assess the feasibility, safety, and efficacy of domiciliary thrombolysis by general practitioners. DESIGN… 
Highly Cited
1988
Highly Cited
1988
The German multicenter trial of anisoylated plasminogen streptokinase activator complex versus heparin for acute myocardial infarction.
Highly Cited
1987
Highly Cited
1987
Anisoylated plasminogen streptokinase activator complex in acute myocardial infarction: a placebo-controlled arteriographic coronary recanalization study.
Highly Cited
1986
Highly Cited
1986
Clinical effects and kinetic properties of intravenous APSAC--anisoylated plasminogen-streptokinase activator complex (BRL 26921) in acute myocardial infarction.
Highly Cited
1986
Highly Cited
1986
Coronary thrombolysis during acute myocardial infarction by intravenous BRL 26921, a new anisoylated plasminogen-streptokinase activator complex.
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