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Ancrod

Known as: Agkistrodon Serine Proteinase, Agkistrododon Protein C Activator, Agkistrododon Rhodostoma Venom Proteinase 
A proteolytic enzyme and defibrinogenating agent derived from the venom of the Malayan pit viper, with profibrinolytic and anticoagulant activities… Expand
National Institutes of Health

Related topics

Related topics

14 relations

Narrower (5)

AaV-SP-II, AgkistrodonArvinArvin IRC-50Venombin A
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Broader (2)

AnticoagulantsFibrinolytic Agents
In BloodProcess of secretionantagonists & inhibitorsaspects of radiation effects
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Rapid identification of thousands of copperhead snake (Agkistrodon contortrix) microsatellite loci from modest amounts of 454 shotgun genome sequence
Optimal integration of next‐generation sequencing into mainstream research requires re‐evaluation of how problems can be… Expand
Highly Cited
2004
Highly Cited
2004
Proteomic characterization of two snake venoms: Naja naja atra and Agkistrodon halys.
Snake venom is a complex mixture of proteins and peptides, and a number of studies have described the biological properties of… Expand
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Highly Cited
2002
Highly Cited
2002
Cloning and characterization of novel snake venom proteins that block smooth muscle contraction.
In this study, we isolated a 25-kDa novel snake venom protein, designated ablomin, from the venom of the Japanese Mamushi snake… Expand
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Highly Cited
2000
Highly Cited
2000
Intravenous ancrod for treatment of acute ischemic stroke: the STAT study: a randomized controlled trial. Stroke Treatment with Ancrod Trial.
CONTEXT Approved treatment options for acute ischemic stroke in the United States and Canada are limited at present to… Expand
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Review
1998
Review
1998
Catastrophic Antiphospholipid Syndrome: Clinical and Laboratory Features of 50 Patients
We analyzed the clinical and laboratory characteristics of 50 patients with catastrophic antiphospholipid syndrome (APS) (5 from… Expand
Review
1993
Review
1993
Heparin-induced thrombocytopenia (HIT): an overview of 230 patients treated with orgaran (Org 10172)
  • H. Magnani
  • Thrombosis and haemostasis
  • 1993
    • Corpus ID: 35634721
Heparin-induced thrombocytopenia (HIT) with thrombosis occurs in about 1 in 2,000 heparin-treated patients. The arterial or… Expand
Highly Cited
1991
Highly Cited
1991
Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia.
In order to determine the efficacy and safety of ancrod, a rapid acting defibrinogenating drug, for patients with heparin-induced… Expand
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Highly Cited
1990
Highly Cited
1990
Platelet glycoprotein IIb-IIIa protein antagonists from snake venoms: evidence for a family of platelet-aggregation inhibitors.
The purification, complete amino acid sequence, and biological activity are described for several homologous snake venom proteins… Expand
Highly Cited
1971
Highly Cited
1971
Bradykinin-potentiating peptides from the venom of Agkistrodon halys blomhoffi. Isolation of five bradykinin potentiators and the amino acid sequences of two of them, potentiators B and C.
Highly Cited
1968
Highly Cited
1968
Therapeutic defibrination in the treatment of thrombotic disease.
Abstract ' Arvin ', the purified active fraction of the venom of Agkistrodon rhodostoma , the Malayan pit-viper, produced… Expand
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