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Ancrod

Known as: Agkistrodon Serine Proteinase, Agkistrododon Protein C Activator, Agkistrododon Rhodostoma Venom Proteinase 
A proteolytic enzyme and defibrinogenating agent derived from the venom of the Malayan pit viper, with profibrinolytic and anticoagulant activities… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1970-2016
05101519702016

Related topics

Related topics

13 relations

Broader (2)

AnticoagulantsFibrinolytic Agents

Narrower (2)

Arvinbrevinase
In BloodProcess of secretionadministration & dosageantagonists & inhibitors
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Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Ancrod
physiological aspects
Anticoagulants
Fibrinolytic Agents
chemical synthesis
standards characteristics

Papers overview

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2009
2009
Ancrod in acute ischemic stroke: results of 500 subjects beginning treatment within 6 hours of stroke onset in the ancrod stroke program.
BACKGROUND AND PURPOSE Previous studies of multiple-day dosing with the defibrinogenating agent, ancrod, in acute ischemic stroke… (More)
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2006
2006
Intravenous ancrod for acute ischaemic stroke in the European Stroke Treatment with Ancrod Trial: a randomised controlled trial.
BACKGROUND Intravenous tissue plasminogen activator is the only approved specific treatment for acute ischaemic stroke. Ancrod, a… (More)
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Highly Cited
2000
Highly Cited
2000
Intravenous ancrod for treatment of acute ischemic stroke: the STAT study: a randomized controlled trial. Stroke Treatment with Ancrod Trial.
CONTEXT Approved treatment options for acute ischemic stroke in the United States and Canada are limited at present to… (More)
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2000
2000
Analysis of fibrin formation and proteolysis during intravenous administration of ancrod.
Ancrod is a purified fraction of venom from the Malayan pit viper, Calloselasma rhodostoma, currently under investigation for… (More)
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1996
1996
Adhesion prevention with ancrod released via a tissue-adherent hydrogel.
The objective of this investigation was to evaluate the effect of ancrod, a fibrinogenolytic protease from Malayan pit viper… (More)
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1992
1992
Heparin, urokinase, and ancrod alter neutrophil function.
Neutrophils (polymorphonuclear neutrophils [PMNs]) have been implicated as mediators of reperfusion injury. Heparin, urokinase… (More)
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1991
1991
Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia.
In order to determine the efficacy and safety of ancrod, a rapid acting defibrinogenating drug, for patients with heparin-induced… (More)
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1989
1989
Ancrod (Arvin) as an alternative to heparin anticoagulation for cardiopulmonary bypass.
Heparin is the anticoagulant used during cardiopulmonary bypass (CPB). Both the use of heparin and the reversal of its effect… (More)
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1983
1983
Controlled trial of ancrod in ischemic stroke.
In a randomized, single-blind study, 30 patients with acute ischemic stroke were treated with either low-molecular weight dextran… (More)
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1976
1976
Defibrination with ancrod in nephrotoxic nephritis in rabbits.
Defibrination with ancrod in nephrotoxic nephritis in rabbits. In rabbits with nephrotoxic nephritis, defibrination with ancrod… (More)
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