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Urokinase

Known as: Urinary Plasminogen Activator, Plasminogen Activator, Urokinase-Type, U-plasminogen activator 
Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor… Expand
National Institutes of Health

Papers overview

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Review
2004
Review
2004
  • M. Duffy
  • Current pharmaceutical design
  • 2004
  • Corpus ID: 23241583
The urokinase plasminogen activator (uPA) system consists of the serine protease uPA, its glycolipid-anchored receptor, uPAR and… Expand
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Highly Cited
2002
Highly Cited
2002
The biochemical basis for the regulation of fibre-type determination in skeletal muscle is not well understood. In addition to… Expand
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Highly Cited
2002
Highly Cited
2002
BACKGROUND Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play essential roles in tumor invasion and… Expand
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Highly Cited
1997
Highly Cited
1997
The molecular mechanisms predisposing to atherosclerotic aneurysm formation remain undefined%1,5. Nevertheless, rupture of aortic… Expand
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Highly Cited
1996
Highly Cited
1996
THE CBP protein acts as a transcriptional adaptor for many different transcription factors by directly contacting DNA-bound… Expand
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Highly Cited
1996
Highly Cited
1996
Abstract Cellular invasion depends on cooperation between adhesive and proteolytic mechanisms. Evidence is provided that the… Expand
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Highly Cited
1994
Highly Cited
1994
Hypersensitive site 2 located in the beta-globin locus control region confers high levels of expression to the genes of the beta… Expand
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Highly Cited
1993
Highly Cited
1993
CYCLIC AMP-regulated gene expression frequently involves a DNA element known as the cAMP-regulated enhancer (CRE)1–4. Many… Expand
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Highly Cited
1992
Highly Cited
1992
The extracellular protease urokinase is known to be crucially involved in morphogenesis, tissue repair and tumor invasion by… Expand
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Highly Cited
1981
Highly Cited
1981
Tumor cells traverse basement membranes (BM) during the stages of the metastatic process. Penetration of the BM may involve… Expand
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