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Urokinase

Known as: Urinary Plasminogen Activator, Plasminogen Activator, Urokinase-Type, U-plasminogen activator 
Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (9)

AbbokinaseAntagosanKidney Plasminogen ActivatorM23 urokinase
Coronary AneurysmCoronary ThrombosisEGF-Like DomainEndothelial Cells

Broader (1)

Serine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1994
Highly Cited
1994
Prognostic impact of urokinase-type plasminogen activator and its inhibitor PAI-1 in completely resected gastric cancer.
The prognostic impact of the proteolytic factors urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitor… 
Highly Cited
1994
Highly Cited
1994
Cartilage chondrolysis by fibronectin fragments is associated with release of several proteinases: stromelysin plays a major role in chondrolysis.
We have reported that three different Fn fragments (Fn-f) added to bovine articular cartilage cultured in serum-free DMEM cause… 
Review
1992
Review
1992
Age Dependence of Ischaemic Heart Syndromes and the Contribution of Haemostatic Deviations
Highly Cited
1991
Highly Cited
1991
Functional analysis of the Drosophila twist promoter reveals a dorsal-binding ventral activator region.
twist is one of the earliest expressed zygotically active genes required for dorsal-ventral pattern formation in the Drosophila… 
Highly Cited
1988
Highly Cited
1988
NifA-dependent in vivo protection demonstrates that the upstream activator sequence of nif promoters is a protein binding site.
Primer-extension analysis of the Klebsiella pneumoniae nifH promoter was used to determine changes in the accessibility of the… 
Highly Cited
1986
Highly Cited
1986
Activation of plasminogen by pro-urokinase. I. Mechanism.
The mechanism of the activation of plasminogen by recombinant pro-urokinase (Rec-pro-UK), obtained by expression of the human pro… 
Highly Cited
1981
Highly Cited
1981
Adsorption to fibrin of native fragments of known primary structure from human plasminogen.
Highly Cited
1979
Highly Cited
1979
Studies on the Fibrinolytic System in Human Plasma: Quantitative Determination of Plasminogen Activators and Proactivators
Summary Effects due to plasma plasminogen activators and proactivators are usually studied in assay systems where inhibitors… 
Highly Cited
1974
Highly Cited
1974
PROPERTIES OF PLASMINOGEN ACTIVATORS FORMED BY NEOPLASTIC HUMAN CELL CULTURES
A series of human cell lines has been examined for fibrinolysis in culture. The sera that are activating for fibrinolysis by… 
Highly Cited
1974
Highly Cited
1974
Physico-chemical and proenzyme properties of NH2-terminal glutamic acid and NH2-terminal lysine human plasminogen. Influence of 6-aminohexanoic acid.
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