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Urokinase

Known as: Urinary Plasminogen Activator, Plasminogen Activator, Urokinase-Type, U-plasminogen activator 
Urokinase-type plasminogen activator (431 aa, ~49 kDa) is encoded by the human PLAU gene. This protein plays a role in both cell surface receptor… 
National Institutes of Health

Related topics

Related topics

46 relations

Narrower (9)

AbbokinaseAntagosanKidney Plasminogen ActivatorM23 urokinase
Coronary AneurysmCoronary ThrombosisEGF-Like DomainEndothelial Cells

Broader (1)

Serine Endopeptidases

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2004
Highly Cited
2004
Population History and Natural Selection Shape Patterns of Genetic Variation in 132 Genes
Identifying regions of the human genome that have been targets of natural selection will provide important insights into human… 
Highly Cited
1999
Highly Cited
1999
Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion.
Activator protein-1 (AP-1) is a transcription factor that consists of either a Jun-Jun homodimer or a Jun-Fos heterodimer… 
Review
1997
Review
1997
Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action.
Steroid/thyroid hormone receptors are ligand-dependent transcription factors that regulate diverse aspects of growth, development… 
Highly Cited
1996
Highly Cited
1996
Transcriptional activation of hedgehog target genes in Drosophila is mediated directly by the cubitus interruptus protein, a member of the GLI family of zinc finger DNA-binding proteins.
Members of the Hedgehog (Hh) family of secreted proteins have been identified recently as key signaling molecules that regulate a… 
Highly Cited
1994
Highly Cited
1994
Characterization of type I receptors for transforming growth factor-beta and activin.
Transforming growth factor-beta (TGF-beta) and activin exert their effects by binding to heteromeric complexes of type I and type… 
Highly Cited
1991
Highly Cited
1991
Cooperative interaction of an initiator-binding transcription initiation factor and the helix–loop–helix activator USF
TRANSCRIPTION initiation by mammalian RNA polymerase II is effected by multiple common factors1,2 interacting through minimal… 
Highly Cited
1988
Highly Cited
1988
Purification and characterization of a plasminogen activator inhibitor 1 binding protein from human plasma. Identification as a multimeric form of S protein (vitronectin).
Highly Cited
1986
Highly Cited
1986
The activation of pro-urokinase by plasma kallikrein and its inactivation by thrombin.
Plasma kallikrein was found to be a good activator of pro-urokinase, the inactive zymogen form of urokinase. The complete… 
Highly Cited
1983
Highly Cited
1983
The binding of human plasminogen to fibrin and fibrinogen.
Highly Cited
1981
Highly Cited
1981
Purification and characterization of the plasminogen activator secreted by human melanoma cells in culture.
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