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protein tyrosine kinase activity
Known as:
protein-tyrosine kinase activity
Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate. [EC:2.7.10]
National Institutes of Health
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Related topics
Related topics
3 relations
Narrower (1)
JAK activity
Broader (1)
peptidyl-tyrosine phosphorylation
regulation of protein tyrosine kinase activity
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
Brain insulin system dysfunction in streptozotocin intracerebroventricularly treated rats generates hyperphosphorylated tau protein
E. Grünblatt
,
M. Salković-Petrisic
,
Jelena S. Osmanović
,
P. Riederer
,
S. Hoyer
Journal of Neurochemistry
2007
Corpus ID: 6831394
The intracerebroventricular (icv) application of streptozotocin (STZ) in low dosage was used in 3‐month‐old rats to explore brain…
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Highly Cited
1996
Highly Cited
1996
Discovery of a Novel, Potent, and Src Family-selective Tyrosine Kinase Inhibitor
J. Hanke
,
J. Gardner
,
+5 authors
P. Connelly
Journal of Biological Chemistry
1996
Corpus ID: 29832169
Here, we have studied the activity of a novel protein-tyrosine kinase inhibitor that is selective for the Src family of tyrosine…
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Highly Cited
1994
Highly Cited
1994
Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes
B. C. Chang
,
J. Fontes
,
M. Peterlin
,
R. Flavell
Journal of Experimental Medicine
1994
Corpus ID: 15092625
The class II transactivator (CIITA) has been shown to be required for major histocompatibility complex (MHC) class II gene…
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Highly Cited
1992
Highly Cited
1992
Mechanism of desensitization of the epidermal growth factor receptor protein-tyrosine kinase.
J. Countaway
,
A. Nairn
,
Roger J. Davis
Journal of Biological Chemistry
1992
Corpus ID: 6814636
Highly Cited
1991
Highly Cited
1991
Molecular cloning of a porcine gene syk that encodes a 72-kDa protein-tyrosine kinase showing high susceptibility to proteolysis.
Takanobu Taniguchi
,
Takashi Kobayashi
,
+7 authors
Hirohei Yamamura
Journal of Biological Chemistry
1991
Corpus ID: 24945806
Highly Cited
1990
Highly Cited
1990
Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins.
B. Druker
,
S. Cannistra
,
Y. Furukawa
,
Y. Torimoto
,
J. Griffin
Blood
1990
Corpus ID: 860992
Human granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-3 (IL-3) exert multiple effects on the…
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Highly Cited
1988
Highly Cited
1988
Platelet-derived growth factor induces multisite phosphorylation of pp60c-src and increases its protein-tyrosine kinase activity
K. Gould
,
T. Hunter
Molecular and Cellular Biology
1988
Corpus ID: 37326743
We have shown previously that pp60c-src is a substrate for protein kinase C in vivo and that the target of protein kinase C…
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Review
1988
Review
1988
Protein Tyrosine Kinase Activity and Its Endogenous Substrates in Rat Brain: A Subcellular and Regional Survey
A. Hirano
,
P. Greengard
,
R. Huganir
Journal of Neurochemistry
1988
Corpus ID: 25553343
Abstract: The rat CNS contains high levels of tyrosine‐specific protein kinases that specifically phosphorylate the tyrosine…
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Highly Cited
1987
Highly Cited
1987
Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin.
C. Chou
,
T. Dull
,
+4 authors
O. Rosen
Journal of Biological Chemistry
1987
Corpus ID: 33655165
Highly Cited
1987
Highly Cited
1987
Point mutation at the ATP binding site of EGF receptor abolishes protein-tyrosine kinase activity and alters cellular routing
A. Honegger
,
T. Dull
,
+6 authors
J. Schlessinger
Cell
1987
Corpus ID: 32077008
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