JAK activity

Known as: JAK, Janus kinase activity 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Extracellular high-mobility group box (HMGB)1 mediates inflammation during sterile and infectious injury and contributes… (More)
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Review
2014
Review
2014
JAK-STAT3 signaling, while regulating many aspects of cancer development and progression, promotes invasion and metastasis… (More)
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2014
2014
The regenerative failure of mammalian optic axons is partly mediated by Socs3-dependent inhibition of Jak/Stat signaling (Smith… (More)
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2014
2014
The mechanisms by which IL-6 contributes to the pathogenesis of chronic inflammatory diseases and cancer are not fully understood… (More)
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2012
2012
Janus kinase (JAK) inhibitors are being developed for the treatment of rheumatoid arthritis, psoriasis, myeloproliferative… (More)
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Review
2009
Review
2009
A number of type 1 receptor cytokine family members protect the heart from acute and chronic oxidative stress. This protection… (More)
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Highly Cited
2009
Highly Cited
2009
BACKGROUND/AIMS We have previously shown that phagocytosis of apoptotic bodies (AB) by hepatic stellate cells (HSC) is… (More)
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Highly Cited
2008
Highly Cited
2008
Postconditioning (POC), a novel strategy of cardioprotection against ischemia-reperfusion injury, is clinically attractive… (More)
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Highly Cited
2006
Highly Cited
2006
The JAK/STAT pathway has pleiotropic roles in animal development, and its aberrant activation is implicated in multiple human… (More)
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Highly Cited
1996
Highly Cited
1996
Receptors for interferons and other cytokines signal through the action of associated protein tyrosine kinases of the JAK family… (More)
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