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prednicarbate

Known as: Pregna-1,4-diene-3,20-dione, 17-((ethoxycarbonyl)oxy)-11-hydroxy-21-(1-oxopropoxy)-, (11beta)-, prednicarbate [Chemical/Ingredient], prednisolone-17-ethylcarbonate-21-propionate 
A synthetic non-halogenated double-ester derivative of the corticosteroid prednisolone with anti-inflammatory, antipruritic and vasoconstrictive… 
National Institutes of Health

Related topics

Related topics

23 relations

Broader (3)

Anti-Inflammatory AgentsGlucocorticoidsprednisolone

Narrower (3)

BatmenDermatopPeitel
Decreased Protein Synthesis [PE]DermatomycosesFacial DermatosesFoot Dermatoses

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Correlation of hydrotropic solubilization by urea with logD of drug molecules and utilization of this effect for topical formulations.
2010
2010
Topical therapy with nadifloxacin cream and prednicarbate cream improves acneiform eruptions caused by the EGFR-inhibitor cetuximab - A report of 29 patients.
The epidermal growth factor receptor (EGFR) inhibitor cetuximab is used to treat advanced stages of solid tumors. Acneiform skin… 
Highly Cited
2008
Highly Cited
2008
Evaluation of beneficial and adverse effects of glucocorticoids on a newly developed full-thickness skin model.
Review
2008
Review
2008
Interventions to reduce Staphylococcus aureus in the management of atopic eczema.
BACKGROUND Staphylococcus aureus can cause secondary infection in atopic eczema, and it may promote inflammation in eczema that… 
Highly Cited
2004
Highly Cited
2004
Glucocorticoid entrapment into lipid carriers--characterisation by parelectric spectroscopy and influence on dermal uptake.
Highly Cited
1997
Highly Cited
1997
Prednicarbate Biotransformation in Human Foreskin Keratinocytes and Fibroblasts
AbstractPurpose. Evaluation of skin layer-specific prednicarbate (PC) biotransformation, possibly explaining the improved benefit… 
1997
1997
Prednicarbate Versus Conventional Topical Glucocorticoids: Pharmacodynamic Characterization In Vitro
AbstractPurpose. Pharmacodynamic characterization of topical glucocorticoids as prednicarbate (PC), its metabolites prednisolone… 
Review
1996
Review
1996
Topical Glucocorticoids with Improved Risk-Benefit Ratio
SummaryTopical glucocorticoids for dermal application were introduced more than 40 years ago and revolutionised the treatment of… 
1993
1993
Prednicarbate activity and benefit/risk ratio in relation to other topical glucocorticoids
Nonhalogenated double esters of prednisolone or hydrocortisone applied topically to the skin have a low atrophogenic potential… 
1988
1988
Influence of corticosteroids on chemotactic response and collagen metabolism of human skin fibroblasts.
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