Author pages are created from data sourced from our academic publisher partnerships and public sources.
Share This Author
Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties.
Lipid nanoparticles for improved topical application of drugs for skin diseases.
Vitamin A loaded solid lipid nanoparticles for topical use: occlusive properties and drug targeting to the upper skin.
Loss of corneodesmosin leads to severe skin barrier defect, pruritus, and atopy: unraveling the peeling skin disease.
Lipid nanoparticles for skin penetration enhancement-correlation to drug localization within the particle matrix as determined by fluorescence and parelectric spectroscopy.
Solid lipid nanoparticles as drug carriers for topical glucocorticoids.
Cyproterone Acetate Loading to Lipid Nanoparticles for Topical Acne Treatment: Particle Characterisation and Skin Uptake
Topical CPA treatment of skin diseases should reduce side effects currently excluding the use in males and demanding contraceptive measures in females and may be an additional therapeutic option for acne and other diseases of the pilosebaceous unit.
Influence of Th2 Cytokines on the Cornified Envelope, Tight Junction Proteins, and ß-Defensins in Filaggrin-Deficient Skin Equivalents.
Immunomodulator FTY720 induces myofibroblast differentiation via the lysophospholipid receptor S1P3 and Smad3 signaling.
This work identified the lysophospholipid receptor S1P3 as the crucial receptor subtype for FTY720-induced myofibroblast differentiation because the effect was abolished in fibroblasts isolated from S 1P3 knockout mice.
Sphingosine 1-phosphate restrains insulin-mediated keratinocyte proliferation via inhibition of Akt through the S1P2 receptor subtype.
- Melanie Schüppel, U. Kürschner, Ulrike Kleuser, M. Schäfer-Korting, B. Kleuser
- BiologyThe Journal of investigative dermatology
- 1 July 2008
Evidence is presented that S1P inhibits insulin-mediated keratinocyte growth via the activation of protein kinase C (PKC) followed by a subsequent dephosphorylation of Akt, which is of great clinical interest.