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potassium channel protein TREK-1

Known as: TREK-1, KCNK2 protein, TREK-1 potassium channel 
National Institutes of Health

Related topics

Related topics

2 relations
KCNK2 gene

Broader (1)

Potassium Channels, Tandem Pore Domain

Papers overview

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Highly Cited
2009
Highly Cited
2009
TWIK-1 and TREK-1 Are Potassium Channels Contributing Significantly to Astrocyte Passive Conductance in Rat Hippocampal Slices
Expression of a linear current–voltage (I–V) relationship (passive) K+ membrane conductance is a hallmark of mature hippocampal… 
Review
2009
Review
2009
The mechano-gated K2P channel TREK-1
The versatility of neuronal electrical activity is largely conditioned by the expression of different structural and functional… 
Review
2009
Review
2009
Two-pore potassium channels in the cardiovascular system
Two-pore domain (K2P) channels emerged about a decade ago and since then have been an expanding area of interest. This is because… 
Highly Cited
2006
Highly Cited
2006
Desensitization of mechano-gated K2P channels.
The neuronal mechano-gated K2P channels TREK-1 and TRAAK show pronounced desensitization within 100 ms of membrane stretch… 
Highly Cited
2006
Highly Cited
2006
The stretch-activated potassium channel TREK-1 in rat cardiac ventricular muscle.
Highly Cited
2006
Highly Cited
2006
AKAP150, a switch to convert mechano‐, pH‐ and arachidonic acid‐sensitive TREK K+ channels into open leak channels
TREK channels are unique among two‐pore‐domain K+ channels. They are activated by polyunsaturated fatty acids (PUFAs) including… 
Highly Cited
2005
Highly Cited
2005
Cross‐talk between the mechano‐gated K2P channel TREK‐1 and the actin cytoskeleton
TREK‐1 (KCNK2) is a K2P channel that is highly expressed in fetal neurons. This K+ channel is opened by a variety of stimuli… 
Highly Cited
2001
Highly Cited
2001
TREK-1 Regulation by Nitric Oxide and cGMP-dependent Protein Kinase
Potassium channels activated by membrane stretch may contribute to maintenance of relaxation of smooth muscle cells in visceral… 
Highly Cited
2001
Highly Cited
2001
Distribution and expression of TREK-1, a two-pore-domain potassium channel, in the adult rat CNS
Highly Cited
2000
Highly Cited
2000
The neuroprotective agent riluzole activates the two P domain K(+) channels TREK-1 and TRAAK.
Riluzole (RP 54274) is a potent neuroprotective agent with anticonvulsant, sedative, and anti-ischemic properties. It is… 
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