potassium channel protein TREK-1

Known as: TREK-1, KCNK2 protein, TREK-1 potassium channel 
 
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Astrocytes release glutamate upon activation of various GPCRs to exert important roles in synaptic functions. However, the… (More)
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Highly Cited
2009
Highly Cited
2009
Expression of a linear current-voltage (I-V) relationship (passive) K(+) membrane conductance is a hallmark of mature hippocampal… (More)
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Highly Cited
2009
Highly Cited
2009
The sensation of cold or heat depends on the activation of specific nerve endings in the skin. This involves heat- and cold… (More)
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Highly Cited
2006
Highly Cited
2006
The TREK-1 channel is a temperature-sensitive, osmosensitive and mechano-gated K+ channel with a regulation by Gs and Gq coupled… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE The biophysical properties and the regulation of the two-pore-domain potassium channel TREK-1 were studied in rat… (More)
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Highly Cited
2006
Highly Cited
2006
Depression is a devastating illness with a lifetime prevalence of up to 20%. The neurotransmitter serotonin or 5… (More)
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Highly Cited
2005
Highly Cited
2005
TREK-1 (KCNK2 or K(2P)2.1) is a mechanosensitive K(2P) channel that is opened by membrane stretch as well as cell swelling. Here… (More)
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Highly Cited
2004
Highly Cited
2004
TREK-1 is a two-pore-domain background potassium channel expressed throughout the central nervous system. It is opened by… (More)
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Highly Cited
2000
Highly Cited
2000
Peripheral and central thermoreceptors are involved in sensing ambient and body temperature, respectively. Specialized cold and… (More)
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Highly Cited
1998
Highly Cited
1998
Tandem pore domain K+ channels represent a new family of ion channels involved in the control of background membrane conductances… (More)
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