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potassium channel protein TREK-1

Known as: TREK-1, KCNK2 protein, TREK-1 potassium channel 
 
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
Astrocytes release glutamate upon activation of various GPCRs to exert important roles in synaptic functions. However, the… Expand
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Highly Cited
2009
Highly Cited
2009
The sensation of cold or heat depends on the activation of specific nerve endings in the skin. This involves heat‐ and cold… Expand
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Highly Cited
2009
Highly Cited
2009
Expression of a linear current–voltage (I–V) relationship (passive) K+ membrane conductance is a hallmark of mature hippocampal… Expand
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Highly Cited
2006
Highly Cited
2006
Depression is a devastating illness with a lifetime prevalence of up to 20%. The neurotransmitter serotonin or 5… Expand
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Highly Cited
2006
Highly Cited
2006
The TREK‐1 channel is a temperature‐sensitive, osmosensitive and mechano‐gated K+ channel with a regulation by Gs and Gq coupled… Expand
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Highly Cited
2004
Highly Cited
2004
TREK‐1 is a two‐pore‐domain background potassium channel expressed throughout the central nervous system. It is opened by… Expand
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Highly Cited
2000
Highly Cited
2000
Peripheral and central thermoreceptors are involved in sensing ambient and body temperature, respectively. Specialized cold and… Expand
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Highly Cited
1999
Highly Cited
1999
Volatile anesthetics produce safe, reversible unconsciousness, amnesia and analgesia via hyperpolarization of mammalian neurons… Expand
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Highly Cited
1999
Highly Cited
1999
TREK-1 is a member of the novel structural class of K+ channels with four transmembrane segments and two pore domains in tandem… Expand
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Highly Cited
1996
Highly Cited
1996
Human TWIK‐1, which has been cloned recently, is a new structural type of weak inward rectifier K+ channel. Here we report the… Expand
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