Skip to search formSkip to main contentSkip to account menu

KCNK2 gene

Known as: TREK-1, K2p2.1, potassium two pore domain channel subfamily K member 2 
National Institutes of Health

Related topics

Related topics

2 relations
KCNK13 genepotassium channel protein TREK-1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2010
Highly Cited
2010
Expression of transient receptor potential channels and two-pore potassium channels in subtypes of vagal afferent neurons in rat.
Vagal afferent neurons relay important information regarding the control of the gastrointestinal system. However, the ionic… 
2009
2009
Pain-associated signals, acidosis and lysophosphatidic acid, modulate the neuronal K2P2.1 channel
2009
2009
Support for the involvement of the KCNK2 gene in major depressive disorder and response to antidepressant treatment
Objective The aim of this study was to examine the associations between genetic variations in the human KCNK2 gene and major… 
2008
2008
Both TASK-3 and TREK-1 two-pore loop K channels are expressed in H295R cells and modulate their membrane potential and aldosterone secretion.
The rate of aldosterone synthesis by adrenal glomerulosa cells relies on the selective permeability of the glomerulosa cell to K… 
2007
2007
Reduced inhibition of cortical glutamate and GABA release by halothane in mice lacking the K+ channel, TREK‐1
Deletion of TREK‐1, a two‐pore domain K+ channel (K2P) activated by volatile anaesthetics, reduces volatile anaesthetic potency… 
2005
2005
The effects of hypoxia on the modulation of human TREK‐1 potassium channels
Two‐pore‐domain potassium channels are a family of ion channels that are widely believed to play an important role in maintaining… 
2004
2004
Trichloroethanol enhances the activity of recombinant human TREK-1 and TRAAK channels
2004
2004
Alterations in the expression of lipid and mechano-gated two-pore domain potassium channel genes in rat brain following chronic cerebral ischemia.
2003
2003
Inhibition of Human TREK-1 Channels by Bupivacaine
Human TWIK-related K+ channels (TREK-1) stabilize the membrane potential (mp) of neurons and have a major role in the regulation… 
Highly Cited
2001
Highly Cited
2001
The neuroprotective agent sipatrigine (BW619C89) potently inhibits the human tandem pore-domain K+ channels TREK-1 and TRAAK
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)