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KCNK2 gene

Known as: TREK-1, K2p2.1, potassium two pore domain channel subfamily K member 2 
 
National Institutes of Health

Papers overview

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Highly Cited
2014
Highly Cited
2014
Significance Mechanical force opens mechanosensitive ion channels in the cellular membrane to produce electrical signals that… Expand
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Highly Cited
2009
Highly Cited
2009
The sensation of cold or heat depends on the activation of specific nerve endings in the skin. This involves heat‐ and cold… Expand
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Review
2007
Review
2007
  • E. Honoré
  • Nature Reviews Neuroscience
  • 2007
  • Corpus ID: 21421846
Two-pore-domain K+ (K2P) channel subunits are made up of four transmembrane segments and two pore-forming domains that are… Expand
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Highly Cited
2006
Highly Cited
2006
The TREK‐1 channel is a temperature‐sensitive, osmosensitive and mechano‐gated K+ channel with a regulation by Gs and Gq coupled… Expand
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Highly Cited
2004
Highly Cited
2004
TREK‐1 is a two‐pore‐domain background potassium channel expressed throughout the central nervous system. It is opened by… Expand
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Review
2000
Review
2000
The two-pore-domain K(+) channels, or K(2P) channels, constitute a novel class of K(+) channel subunits. They have four… Expand
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Highly Cited
2000
Highly Cited
2000
Mechano-sensitive and fatty acid-activated K+ belong to the structural class of K+channel with two pore domains. Here, we report… Expand
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Highly Cited
2000
Highly Cited
2000
Peripheral and central thermoreceptors are involved in sensing ambient and body temperature, respectively. Specialized cold and… Expand
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Highly Cited
1999
Highly Cited
1999
Volatile anesthetics produce safe, reversible unconsciousness, amnesia and analgesia via hyperpolarization of mammalian neurons… Expand
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Highly Cited
1996
Highly Cited
1996
Human TWIK‐1, which has been cloned recently, is a new structural type of weak inward rectifier K+ channel. Here we report the… Expand
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