oblimersen

Known as: olbimersen, BCL2 Gene Anticode Oligodeoxynucleotide, 5'-tct ccc agc gtg cgc cat 
A phosphorothioate antisense oligonucleotide. Targeted to the initiation codon region of the bcl-2 mRNA, oblimersen inhibits bcl-2 mRNA translation… (More)
National Institutes of Health

Papers overview

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2010
2010
A circular code is a set of trinucleotides allowing the reading frames in genes to be retrieved locally, i.e. anywhere in genes… (More)
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Highly Cited
2009
Highly Cited
2009
PURPOSE A randomized trial of oblimersen plus fludarabine/cyclophosphamide (OBL-FC; n = 120) versus FC (n = 121) was conducted in… (More)
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2009
2009
PURPOSE In a randomised study (GM301; dacarbazine with/without oblimersen), patients with advanced melanoma were stratified based… (More)
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2009
2009
PURPOSE This study aimed to investigate the expression of the ErbB family of receptor tyrosine kinases in pulmonary typical… (More)
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Highly Cited
2008
Highly Cited
2008
PURPOSE To assess the efficacy and toxicity of carboplatin, etoposide, and the bcl-2 antisense oligonucleotide oblimersen as… (More)
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2008
2008
Diphtheria is caused by both toxigenic Corynebacterium diphtheriae and Corynebacterium ulcerans strains harboring lysogenic, tox… (More)
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2007
2007
Among adults in Western countries, chronic lymphocytic leukemia (CLL) is the most prevalent form of leukemia. CLL primarily… (More)
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2006
2006
PURPOSE To determine whether the combination of the proteasome inhibitor bortezomib and the bcl-2 antisense molecule oblimersen… (More)
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2003
2003
G3139 is an 18-mer phosphorothioate oligodeoxyribonucleotide, which is targeted to the initiation codon region of the bcl-2mRNA… (More)
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Highly Cited
1998
Highly Cited
1998
Expression of Bcl-2 is life-sustaining for small-cell lung cancer cells and associated with drug resistance. In the present study… (More)
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