Translational Repression

Known as: Protein Synthesis Inhibition, Translational Inhibition 
Translational Repression consists of cellular and enzymatic reactions that inhibit the process by which polypeptides are synthesized on ribosomes… (More)
National Institutes of Health

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Papers overview

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Highly Cited
2012
Highly Cited
2012
miRNA-mediated gene silencing by translational repression followed by mRNA deadenylation and decay.
microRNAs (miRNAs) regulate gene expression through translational repression and/or messenger RNA (mRNA) deadenylation and decay… (More)
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Highly Cited
2012
Highly Cited
2012
Sustained translational repression by eIF2α-P mediates prion neurodegeneration
The mechanisms leading to neuronal death in neurodegenerative disease are poorly understood. Many of these disorders, including… (More)
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Review
2011
Review
2011
Gene silencing by microRNAs: contributions of translational repression and mRNA decay
Despite their widespread roles as regulators of gene expression, important questions remain about target regulation by microRNAs… (More)
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Highly Cited
2009
Highly Cited
2009
Angiogenin cleaves tRNA and promotes stress-induced translational repression
Stress-induced phosphorylation of eIF2alpha inhibits global protein synthesis to conserve energy for repair of stress-induced… (More)
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Highly Cited
2009
Highly Cited
2009
Biochemical evidence for translational repression by Arabidopsis microRNAs.
MicroRNAs (miRNAs) regulate gene expression posttranscriptionally through RNA silencing, a mechanism conserved in eukaryotes… (More)
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Highly Cited
2008
Highly Cited
2008
Widespread translational inhibition by plant miRNAs and siRNAs.
High complementarity between plant microRNAs (miRNAs) and their messenger RNA targets is thought to cause silencing, prevalently… (More)
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Highly Cited
2008
Highly Cited
2008
GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay
MicroRNAs (miRNAs) silence gene expression by binding 3′ untranslated regions of target mRNAs. Recent studies suggested silencing… (More)
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Highly Cited
2006
Highly Cited
2006
Regulation of sexual development of Plasmodium by translational repression.
Translational repression of messenger RNAs (mRNAs) plays an important role in sexual differentiation and gametogenesis in… (More)
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Highly Cited
2005
Highly Cited
2005
General Translational Repression by Activators of mRNA Decapping
Translation and mRNA degradation are affected by a key transition where eukaryotic mRNAs exit translation and assemble an mRNP… (More)
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Highly Cited
2004
Highly Cited
2004
Specificity of microRNA target selection in translational repression.
MicroRNAs (miRNAs) are a class of noncoding RNAs found in organisms as evolutionarily distant as plants and mammals, yet most of… (More)
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